| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Urology & Nephrology |
| Manuscript Type |
Review |
| Article Title |
Beyond glycemic control: Roles of sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide-1 receptor agonists in diabetic kidney disease
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Gabriel LC Santos, Clara FSM dos Santos, Gabriel R Rocha, Mariana S Calmon, Fabian FB Lemos, Luis GO Silva, Marcel S Luz, Samuel LR Pinheiro, Anelise CS Botelho and Fabrício F de Melo |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Industrial Technological Initiation Scholarship of National Council for Scientific and Technological Development, CNPq, Brazil |
0932204294929829 and 7414780530977345 |
| the Scientific Initiation Scholarship Programme (PIBIC) of National Council for Scientific and Technological Development, CNPq, Brazil |
5763023359532159 and 6472982965854452 |
| the Scientific Initiation Scholarship Programme (PIBIC) of National Council for Scientific and Technological Development, CNPq, Brazil |
7340128440641417 |
| the CNPq Research Productivity Fellow |
4357511882624145 |
|
| Corresponding Author |
Fabrício F de Melo, PhD, Professor, Instituto Multidisciplinar em Saúde, Universidade Federal da Bahia, Rua Hormindo Barros, 58, Quadra 17, Lote 58, Vitória da Conquista 45029-094, Bahia, Brazil. freiremeloufba@gmail.com |
| Key Words |
Sodium-glucose cotransporter 2 inhibitors; Glucagon-like peptide-1 receptor agonists; chronic kidney disease; diabetic kidney disease; Type 2 diabetes; diabetes mellitus |
| Core Tip |
Diabetes is the leading cause of chronic kidney disease and treatment options for renal impairment caused by it were limited until recently. Over the past decade, research in this field has expanded considerably, incorporating several new therapies with proven benefits in slowing down kidney disease progression, especially sodium-glucose cotransporter 2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists. Understanding the state of research with these therapies and clinical recommendations for their use in the context of diabetic kidney disease is a crucial step in providing optimized treatment options for patients with this condition. |
| Publish Date |
2025-06-13 11:47 |
| Citation |
<p>Santos GL, dos Santos CF, Rocha GR, Calmon MS, Lemos FF, Silva LG, Luz MS, Pinheiro SL, Botelho AC, de Melo FF. Beyond glycemic control: Roles of sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide-1 receptor agonists in diabetic kidney disease. <i>World J Diabetes</i> 2025; 16(6): 104706</p> |
| URL |
https://www.wjgnet.com/1948-9358/full/v16/i6/104706.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v16.i6.104706 |
