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5/26/2025 9:22:13 AM | Browse: 33 | Download: 87
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Received |
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2025-01-03 15:56 |
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Peer-Review Started |
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2025-01-03 15:56 |
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To Make the First Decision |
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Return for Revision |
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2025-03-28 00:47 |
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Revised |
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2025-04-09 11:37 |
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Second Decision |
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2025-05-08 02:48 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-05-08 08:53 |
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Articles in Press |
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2025-05-08 08:53 |
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Publication Fee Transferred |
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2025-04-14 02:14 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-05-21 00:49 |
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Publish the Manuscript Online |
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2025-05-26 07:26 |
ISSN |
1949-8470 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Radiology, Nuclear Medicine & Medical Imaging |
Manuscript Type |
Retrospective Study |
Article Title |
Computed tomography-guided percutaneous biopsy for assessing tumor heterogeneity in neuroendocrine tumor metastases to the liver
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Lei-Lei Ying, Ke-Ning Li, Wen-Tao Li, Xin-Hong He and Chao Chen |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China |
No. 82072034 |
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Corresponding Author |
Chao Chen, PhD, Department of Interventional Radiology, Fudan University Shanghai Cancer Center, No. 270 Dongan Road, Xuhui District, Shanghai 200032, China. chaochen_cc@fudan.edu.cn |
Key Words |
Image-guided core needle biopsy; Gastroenteropancreatic neuroendocrine tumors; Liver metastases; Survival; Tumor heterogeneity |
Core Tip |
This study demonstrates that percutaneous computed tomography-guided core needle biopsy effectively identifies clinically significant grading heterogeneity in liver metastases from gastroenteropancreatic neuroendocrine tumors. Notably, 40.2% of patients exhibited grade discrepancies between primary and metastatic sites, with upgraded tumors (e.g., G2 to G3) correlating with markedly reduced overall survival. These findings emphasize percutaneous computed tomography-guided core needle biopsy’s pivotal role in optimizing risk stratification, informing personalized therapeutic decisions (e.g., intensified surveillance or targeted therapies), and improving prognostic accuracy for gastroenteropancreatic neuroendocrine tumor patients, while confirming its safety and diagnostic reliability in clinical practice. |
Publish Date |
2025-05-26 07:26 |
Citation |
<p>Ying LL, Li KN, Li WT, He XH, Chen C. Computed tomography-guided percutaneous biopsy for assessing tumor heterogeneity in neuroendocrine tumor metastases to the liver. <i>World J Radiol</i> 2025; 17(5): 104808</p> |
URL |
https://www.wjgnet.com/1949-8470/full/v17/i5/104808.htm |
DOI |
https://dx.doi.org/10.4329/wjr.v17.i5.104808 |
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