Publication Name	World Journal of Cardiology
Manuscript ID	104832
Country	China

Received	2025-01-08 09:23
Peer-Review Started	2025-01-08 09:23
To Make the First Decision
Return for Revision	2025-02-14 09:11
Revised	2025-02-26 18:40
Second Decision	2025-05-12 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-05-13 00:58
Articles in Press	2025-05-13 00:58
Publication Fee Transferred	2025-03-03 02:41
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-06-09 11:54
Publish the Manuscript Online	2025-06-20 07:30

ISSN	1949-8462 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Basic Study
Article Title	Hydrogen alleviates right ventricular hypertrophy by inhibiting ferroptosis via restoration of the Nrf2/HO-1 signaling pathway
Manuscript Source	Unsolicited Manuscript
All Author List	Jun-Cai Bai, Hong-Xiao Yang, Cheng-Chuang Zhan, Lu-Qi Zhao, Jia-Ren Liu and Wei Yang
Funding Agency and Grant Number
Corresponding Author	Wei Yang, MD, Department of Cardiology, the Fourth Affiliated Hospital of Harbin Medical University, No. 37 Yiyuan Street, Harbin 150000, Heilongjiang Province, China. weiyangyangwei@yeah.net
Key Words	Hydrogen; Right ventricular hypertrophy; Nrf2/HO-1; Ferroptosis
Core Tip	This study explored the protective effects of hydrogen (H₂) on right ventricular hypertrophy (RVH) both in vivo and in vitro. The results revealed that H₂ inhibited ferroptosis, an iron-dependent cell death, by restoring the Nrf2/HO-1 pathway, offering new insights for treating RVH.
Publish Date	2025-06-20 07:30
Citation	<p>Bai JC, Yang HX, Zhan CC, Zhao LQ, Liu JR, Yang W. Hydrogen alleviates right ventricular hypertrophy by inhibiting ferroptosis via restoration of the Nrf2/HO-1 signaling pathway. <i>World J Cardiol</i> 2025; 17(6): 104832</p>
URL	https://www.wjgnet.com/1949-8462/full/v17/i6/104832.htm
DOI	https://dx.doi.org/10.4330/wjc.v17.i6.104832

Full Article (PDF)	WJC-17-104832-with-cover.pdf
The ARRIVE Guidelines	104832-The-ARRIVE-Guidelines.pdf
Manuscript File	104832_Auto_Edited_064310.docx
Answering Reviewers	104832-answering-reviewers.pdf
Audio Core Tip	104832-audio.mp3
Biostatistics Review Certificate	104832-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	104832-conflict-of-interest-statement.pdf
Copyright License Agreement	104832-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	104832-institutional-animal-care-and-use-committee-statement.pdf
Institutional Review Board Approval Form or Document	104832-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	104832-non-native-speakers.pdf
Peer-review Report	104832-peer-reviews.pdf
Scientific Editor Work List	104832-scientific-editor-work-list.pdf
CrossCheck Report	104832-crosscheck-report.pdf