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4/18/2025 9:39:02 AM | Browse: 325 | Download: 886
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Received |
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2025-01-05 14:25 |
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Peer-Review Started |
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2025-01-05 14:26 |
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First Decision by Editorial Office Director |
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2025-02-13 22:30 |
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Return for Revision |
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2025-02-13 22:30 |
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Revised |
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2025-02-24 13:43 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-03-24 02:37 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-03-24 08:02 |
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Articles in Press |
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2025-03-24 08:02 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-04-07 10:43 |
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Publish the Manuscript Online |
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2025-04-18 07:43 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Neurosciences |
| Manuscript Type |
Basic Study |
| Article Title |
Rhapontin activates nuclear factor erythroid 2-related factor 2 to ameliorate 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced gastrointestinal dysfunction in Parkinson's disease mice
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xin-Yu Wang, Fang Liu, Qi-Tong Wang, Shu-Zhu Li, Yu-Zhao Ye, Tao Chen and Ben-Chi Cai |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Hainan Provincial Natural Science Foundation of China |
823MS133 and 821QN0979 |
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| Corresponding Author |
Ben-Chi Cai, Professor, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Hainan Medical University, No. 19 Xiuhua Road, Xiuying District, Haikou 570100, Hainan Province, China. caibenchi@hainmc.edu.cn |
| Key Words |
Rhapontin; Gastrointestinal dysfunction; Parkinson’s disease; Nuclear factor erythroid 2-related factor 2; Gut-Brain axis; Oxidative stress; Neuroinflammation |
| Core Tip |
The specific objectives of this study are to identify key molecular targets of rhapontin, evaluate its impact on gastrointestinal symptoms in Parkinson's disease, and investigate its anti-inflammatory effects mediated by nuclear factor erythroid 2-related factor 2 activation. |
| Publish Date |
2025-04-18 07:43 |
| Citation |
Wang XY, Liu F, Wang QT, Li SZ, Ye YZ, Chen T, Cai BC. Rhapontin activates nuclear factor erythroid 2-related factor 2 to ameliorate 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced gastrointestinal dysfunction in Parkinson's disease mice. World J Gastroenterol 2025; 31(15): 104875
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| URL |
https://www.wjgnet.com/1007-9327/full/v31/i15/104875.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i15.104875 |
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