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5/15/2025 12:25:58 PM | Browse: 23 | Download: 48
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Received |
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2025-01-09 06:11 |
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Peer-Review Started |
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2025-01-09 06:11 |
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To Make the First Decision |
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Return for Revision |
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2025-02-14 07:24 |
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Revised |
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2025-03-07 13:33 |
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Second Decision |
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2025-03-25 02:37 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-03-25 06:56 |
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Articles in Press |
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2025-03-25 06:56 |
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Publication Fee Transferred |
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2025-03-11 07:24 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-04-27 04:13 |
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Publish the Manuscript Online |
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2025-05-15 10:28 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Evaluation of efficacy and safety of targeted therapy and immune checkpoint inhibitors in metastatic colorectal cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Peng-Jian Wang, Jing Wang, Xue-Min Yao, Wei-Li Cheng, Lu Sun, Jie Yan, Yong-Ling Yu, Su-Yao Li, Da-Peng Li and Jing-Hao Jia |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Hebei Provincial Medical Science Research Project Program |
20240164 |
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| Corresponding Author |
Da-Peng Li, Chief Physician, Department of Digestive Oncology, Tianjin Tumor Hospital Qinhuangdao Hospital, No. 64 Guangming Road, Haigang District, Qinhuangdao 066000, Hebei Province, China, Qinhuangdao 066000, Hebei Province, China. 15232330077@163.com |
| Key Words |
Metastatic colorectal cancer; Targeted therapy; Immune checkpoint inhibitors; Progression-free survival; Combination therapy |
| Core Tip |
This study demonstrates that combining targeted therapy with immune checkpoint inhibitors significantly improves progression-free survival in patients with metastatic colorectal cancer (mCRC). The study also highlights the manageable safety profile of the combination therapy, offering a potential new approach for advanced mCRC treatment. Further research is needed to confirm these findings in larger trials. |
| Publish Date |
2025-05-15 10:28 |
| Citation |
<p>Wang PJ, Wang J, Yao XM, Cheng WL, Sun L, Yan J, Yu YL, Li SY, Li DP, Jia JH. Evaluation of efficacy and safety of targeted therapy and immune checkpoint inhibitors in metastatic colorectal cancer. <i>World J Gastrointest Oncol</i> 2025; 17(5): 105027</p> |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i5/105027.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i5.105027 |
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