Publication Name	World Journal of Radiology
Manuscript ID	105059
Country	China

Received	2025-01-10 09:07
Peer-Review Started	2025-01-10 09:07
To Make the First Decision
Return for Revision	2025-01-24 04:09
Revised	2025-01-26 18:08
Second Decision	2025-02-14 02:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-02-14 07:27
Articles in Press	2025-02-14 07:27
Publication Fee Transferred	2025-01-31 11:29
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-02-21 03:15
Publish the Manuscript Online	2025-02-26 08:32

ISSN	1949-8470 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Infectious Diseases
Manuscript Type	Case Report
Article Title	Treatment of a rare and severe infection of central nervous system by Angiostrongylus cantonensis: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Jian-Hui Zhao, Wen-Ju Li, Jie Jiao, Ming-Xing Wang, Xi-Mu Zhang, Jian-Yuan Yin, Wen-Zhi Hu, Qing Song and Jie Liu
Funding Agency and Grant Number	Funding Agency Grant Number Hainan Provincial Natural Science Foundation of China No. 824MS173 Hainan Provincial Natural Science Foundation of China No. 823MS165 Project supported by Hainan Province Clinical Medical Center
Corresponding Author	Jie Liu, Director, PhD, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, No. 80 Jianglin Road, Haitang District, Sanya 572013, Hainan Province, China. liujie20231974@163.com
Key Words	Angiostrongylus cantonensis; Cerebrospinal meningitis; Severe infection; Central nervous system; Metagenomics next generation sequencing; Case report
Core Tip	A 20-year-old male developed persistent neck and back pain, urinary retention, and low fever after consuming raw snail meat. Initially misdiagnosed with viral infection and Mycobacterium tuberculosis in the central nervous system, the patient was later confirmed to have angiostrongylus cantonensis infection via metagenomics next-generation sequencing. Effective antiparasitic treatment with albendazole, ceftriaxone, and methylprednisolone led to successful weaning from mechanical ventilation and transfer out of the intensive care unit for hyperbaric oxygen and rehabilitation treatment. This case highlights the diagnostic challenges of angiostrongylus cantonensis infection and the importance of advanced sequencing techniques in identifying rare pathogens.
Publish Date	2025-02-26 08:32
Citation	<p>Zhao JH, Li WJ, Jiao J, Wang MX, Zhang XM, Yin JY, Hu WZ, Song Q, Liu J. Treatment of a rare and severe infection of central nervous system by Angiostrongylus cantonensis: A case report. <i>World J Radiol</i> 2025; 17(2): 105059</p>
URL	https://www.wjgnet.com/1949-8470/full/v17/i2/105059.htm
DOI	https://dx.doi.org/10.4329/wjr.v17.i2.105059

Full Article (PDF)	WJR-17-105059-with-cover.pdf
CARE Checklist–2016	105059-CARE-Checklist-2016.pdf
Manuscript File	105059_Auto_Edited_012631.docx
Answering Reviewers	105059-answering-reviewers.pdf
Audio Core Tip	105059-audio.wav
Conflict-of-Interest Disclosure Form	105059-conflict-of-interest-statement.pdf
Copyright License Agreement	105059-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	105059-foundation-statement.pdf
Signed Consent for Treatment Form(s) or Document(s)	105059-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate	105059-non-native-speakers.pdf
Peer-review Report	105059-peer-reviews.pdf
Scientific Misconduct Check	105059-scientific-misconduct-check.png
Scientific Editor Work List	105059-scientific-editor-work-list.pdf
CrossCheck Report	105059-crosscheck-report.png
CrossCheck Report	105059-crosscheck-report.pdf