Publication Name	World Journal of Orthopedics
Manuscript ID	105130
Country	China

Received	2025-01-13 07:36
Peer-Review Started	2025-01-13 07:36
To Make the First Decision
Return for Revision	2025-01-24 07:30
Revised	2025-01-25 11:44
Second Decision	2025-02-17 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-02-17 09:04
Articles in Press	2025-02-17 09:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-02-20 01:36
Publish the Manuscript Online	2025-03-12 05:57

ISSN	2218-5836 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Orthopedics
Manuscript Type	Letter to the Editor
Article Title	Optimization and advances in negative pressure wound therapy for the management of necrotizing fasciitis in the upper limb
Manuscript Source	Unsolicited Manuscript
All Author List	Peng Wang, Zhi-Peng Li, Yu-Hua Ruan, Peng Yan, Wei-Ping Fu and Chang-Jiang Zhang
Funding Agency and Grant Number	Funding Agency Grant Number Henan Province Key Research and Development Program 231111311000 Henan Provincial Science and Technology Research Project 232102310411 Henan Province Medical Science and Technology Key Project LHGJ20220566 Henan Province Medical Science and Technology Key Project LHGJ20240365 Henan Province Medical Education Research Project WJLX2023079 Zhengzhou Medical and Health Technology Innovation Guidance Program 2024YLZDJH022
Corresponding Author	Chang-Jiang Zhang, Chief Physician, MD, Professor, Second Department of Orthopedics, The Fifth Affiliated Hospital of Zhengzhou University, No.3 Kangfu Qianjie, Erqi District, Zhengzhou 450052, Henan Province, China. changjiangzhang1968@outlook.com
Key Words	Artificial intelligence; Biomaterials; Hyperbaric oxygen therapy; Necrotizing fasciitis; Negative pressure wound therapy; Personalized medicine; Tissue engineering; Wound healing
Core Tip	This study explores the optimization of negative pressure wound therapy (NPWT) for the management of upper limb necrotizing fasciitis (NF), a life-threatening condition. It highlights the advantages of NPWT in accelerating wound healing and improving functional outcomes while addressing its limitations. Key innovations discussed include adaptive NPWT with dynamic pressure regulation, adjunctive therapies such as platelet-rich plasma and antimicrobial dressings, and the integration of advanced technologies like artificial intelligence, imaging modalities, and biomaterials. The findings emphasize the importance of personalized, multidisciplinary approaches and emerging technologies in enhancing treatment efficacy and global standardization of care for NF.
Publish Date	2025-03-12 05:57
Citation	<p>Wang P, Li ZP, Ruan YH, Yan P, Fu WP, Zhang CJ. Optimization and advances in negative pressure wound therapy for the management of necrotizing fasciitis in the upper limb. <i>World J Orthop</i> 2025; 16(3): 105130</p>
URL	https://www.wjgnet.com/2218-5836/full/v16/i3/105130.htm
DOI	https://dx.doi.org/10.5312/wjo.v16.i3.105130

Full Article (PDF)	WJO-16-105130-with-cover.pdf
Manuscript File	105130_Auto_Edited_083320.docx
Answering Reviewers	105130-answering-reviewers.pdf
Audio Core Tip	105130-audio.mp3
Conflict-of-Interest Disclosure Form	105130-conflict-of-interest-statement.pdf
Copyright License Agreement	105130-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	105130-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	105130-non-native-speakers.pdf
Peer-review Report	105130-peer-reviews.pdf
Scientific Misconduct Check	105130-scientific-misconduct-check.png
Scientific Editor Work List	105130-scientific-editor-work-list.pdf
CrossCheck Report	105130-crosscheck-report.pdf