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8/12/2025 2:21:09 PM | Browse: 34 | Download: 195
Publication Name World Journal of Experimental Medicine
Manuscript ID 105208
Country India
Received
2025-01-15 12:30
Peer-Review Started
2025-01-18 08:46
To Make the First Decision
Return for Revision
2025-04-09 01:32
Revised
2025-04-22 12:07
Second Decision
2025-06-19 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-06-20 01:48
Articles in Press
2025-06-20 01:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-08-04 01:50
Publish the Manuscript Online
2025-08-12 08:18
ISSN 2220-315x (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Case Control Study
Article Title Evaluation of urinary extracellular vesicles and microRNAs to diagnose urogenital tuberculosis
Manuscript Source Invited Manuscript
All Author List Parijat Das, Dharmendra K Chaudhary, Richa Mishra and Swasti Tiwari
Funding Agency and Grant Number
Funding Agency Grant Number
Indian Council of Medical Research No. Coord/7 (1)/CARE-KD/18-NCD-II
Corresponding Author Swasti Tiwari, Department of Molecular Medicine and Biotechnology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Mawaiya, Lucknow 226014, Uttar Pradesh, India. tiwari.pgi@gmail.com
Key Words Tuberculosis; Urine; Extracellular vesicles; MicroRNA; Biomarker
Core Tip Discovery of new biomarkers from easily attainable bodily fluids is essential for controlling Urogenital tuberculosis (TB), a significant health concern. Urinary extracellular vesicle microRNAs (miRNAs) are exciting as biomarkers given their stability and non-invasive nature. miRNA-155, miRNA-26 and miRNA-29 play a crucial role in mycobacterium TB pathogenesis via regulation of posttranscriptional gene expression and subsequently apoptosis, cellular proliferation, differentiation and several other biological functions governing various facets of innate and acquired immunity. Thus, there is scope for developing miRNA studies using in vitro and in vivo models in TB which would likely lead to new technologies in diagnosis and treatment.
Publish Date 2025-08-12 08:18
Citation <p>Das P, Chaudhary DK, Mishra R, Tiwari S. Evaluation of urinary extracellular vesicles and microRNAs to diagnose urogenital tuberculosis. <i>World J Exp Med</i> 2025; 15(3): 105208</p>
URL https://www.wjgnet.com/2220-315X/full/v15/i3/105208.htm
DOI https://dx.doi.org/10.5493/wjem.v15.i3.105208
Full Article (PDF) WJEM-15-105208-with-cover.pdf
STROBE Statement 105208-STROBE-statement.pdf
Manuscript File 105208_Auto_Edited_080017.docx
Answering Reviewers 105208-answering-reviewers.pdf
Audio Core Tip 105208-audio.mp3
Biostatistics Review Certificate 105208-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 105208-conflict-of-interest-statement.pdf
Copyright License Agreement 105208-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 105208-foundation-statement.pdf
Signed Informed Consent Form(s) or Document(s) 105208-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 105208-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 105208-non-native-speakers.pdf
Supplementary Material 105208-supplementary-material.pdf
Peer-review Report 105208-peer-reviews.pdf
Scientific Misconduct Check 105208-scientific-misconduct-check.png
Scientific Editor Work List 105208-scientific-editor-work-list.pdf
CrossCheck Report 105208-crosscheck-report.pdf