| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Multiparametric ultrasound for non-invasive assessment of liver steatosis, fibrosis and inflammation in metabolic dysfunction-associated steatotic liver disease
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Antonio Liguori, Maria E Ainora, Luca Di Gialleonardo, Nicholas Viceconti, Lucrezia Petrucci, Giorgio Esposto, Maria C Giustiniani, Irene Mignini, Raffaele Borriello, Linda Galasso, Mattia Paratore, Matteo Garcovich, Laura Riccardi, Maurizio Pompili, Antonio Grieco, Antonio Gasbarrini, Luca Miele and Maria A Zocco |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Maria A Zocco, MD, PhD, Professor, CEMAD, Centro Malattie Apparato Digerente, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Gemelli 1, Rome 00168, Italy. mariaassunta.zocco@unicatt.it |
| Key Words |
Metabolic dysfunction-associated steatotic liver disease; Multiparametric ultrasound; Liver fibrosis; Liver viscosity; Liver inflammation |
| Core Tip |
This article provides further insights on performance of different ultrasound-based techniques for non-invasive multiparametric assessment of liver fibrosis, steatosis, and inflammation in patients with metabolic dysfunction-associated steatotic liver disease. We found that among the analyzed parameters, liver viscosity was associated with the degree of inflammation and ballooning and allows, together with ultrasound attenuation and biochemical parameters, to identify patients with metabolic dysfunction-associated steatohepatitis (MASH) with a good reliability. This could help to distinguish patients at high risk from those at low risk, and therefore it could reduce the number of liver biopsies in patients at low risk of MASH. |
| Publish Date |
2025-07-04 09:23 |
| Citation |
<p>Liguori A, Ainora ME, Di Gialleonardo L, Viceconti N, Petrucci L, Esposto G, Giustiniani MC, Mignini I, Borriello R, Galasso L, Paratore M, Garcovich M, Riccardi L, Pompili M, Grieco A, Gasbarrini A, Miele L, Zocco MA. Multiparametric ultrasound for non-invasive assessment of liver steatosis, fibrosis and inflammation in metabolic dysfunction-associated steatotic liver disease. <i>World J Gastroenterol</i> 2025; 31(25): 105518</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i25/105518.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i25.105518 |
