Publication Name	World Journal of Clinical Cases
Manuscript ID	105596
Country	Pakistan

Received	2025-01-30 06:45
Peer-Review Started	2025-01-30 06:45
To Make the First Decision
Return for Revision	2025-03-27 10:20
Revised	2025-03-29 07:58
Second Decision	2025-04-10 03:10
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-04-11 02:39
Articles in Press	2025-04-11 02:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-05-05 11:13
Publish the Manuscript Online	2025-05-14 05:24

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Mediastinal lymphadenopathy: Causes, symptoms and factors predicting good yield of endoscopic ultrasound-guided biopsy
Manuscript Source	Invited Manuscript
All Author List	Abbas A Tasneem, Nasir H Luck and Muhammed Mubarak
Funding Agency and Grant Number
Corresponding Author	Muhammed Mubarak, Professor, Department of Histopathology, Sindh Institute of Urology and Transplantation, Chand Bibi Road, Karachi 74200, Sindh, Pakistan. drmubaraksiut@yahoo.com
Key Words	Mediastinal lymphadenopathy; Endoscopic ultrasound; Causes; Biopsy
Core Tip	Endoscopic ultrasound effectively diagnoses causes of enlarged mediastinal lymph nodes (MLNs), including tuberculosis, anthracosis, and metastatic diseases, with over half of cases lacking chest-related symptoms. Factors predicting good diagnostic yield include MLN size > 12 mm, subcarinal location, use of fine-needle biopsy over fine-needle aspiration, and satisfactory macroscopic on-site evaluation (MOSE). Larger MLNs and optimal MOSE were the strongest predictors on multivariate analysis, emphasizing the importance of accurate imaging and procedural technique in achieving reliable diagnostic outcomes.
Publish Date	2025-05-14 05:24
Citation	<p>Tasneem AA, Luck NH, Mubarak M. Mediastinal lymphadenopathy: Causes, symptoms and factors predicting good yield of endoscopic ultrasound-guided biopsy. <i>World J Clin Cases</i> 2025; 13(22): 105596</p>
URL	https://www.wjgnet.com/2307-8960/full/v13/i22/105596.htm
DOI	https://dx.doi.org/10.12998/wjcc.v13.i22.105596

Full Article (PDF)	WJCC-13-105596-with-cover.pdf
STROBE Statement	105596-STROBE-statement.pdf
Manuscript File	105596_Auto_Edited_042407.docx
Answering Reviewers	105596-answering-reviewers.pdf
Audio Core Tip	105596-audio.opus
Biostatistics Review Certificate	105596-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	105596-conflict-of-interest-statement.pdf
Copyright License Agreement	105596-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	105596-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	105596-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	105596-non-native-speakers.pdf
Peer-review Report	105596-peer-reviews.pdf
Scientific Misconduct Check	105596-scientific-misconduct-check.png
Scientific Editor Work List	105596-scientific-editor-work-list.pdf
CrossCheck Report	105596-crosscheck-report.pdf