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6/13/2025 2:04:46 PM | Browse: 26 | Download: 67
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Received |
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2025-02-05 04:42 |
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Peer-Review Started |
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2025-02-05 04:42 |
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To Make the First Decision |
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Return for Revision |
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2025-03-19 08:55 |
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2025-03-27 02:43 |
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Second Decision |
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2025-04-21 13:27 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-05-16 08:52 |
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Articles in Press |
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2025-05-16 08:52 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-06-06 01:17 |
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Publish the Manuscript Online |
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2025-06-13 11:47 |
ISSN |
1948-9358 (online) |
Open Access |
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Endocrinology & Metabolism |
Manuscript Type |
Minireviews |
Article Title |
Autophagy in Schwann cells: A potential pharmacotherapeutic target in diabetic peripheral neuropathy
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Manuscript Source |
Invited Manuscript |
All Author List |
Qi-Chang Xing, Jia Chen, Zheng Liu, Wen-Can Li, Xiang Liu and Wei Li |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Natural Science Foundation of Hunan Province |
2023JJ60497 |
Chinese Medicine Research Program of Hunan Province |
2021169 |
Xiangtan Medical Research Project Plan |
2022-xtyx-34 and 2022-xtyx-36 |
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Corresponding Author |
Qi-Chang Xing, Assistant Professor, Department of Clinical Pharmacy, Xiangtan Central Hospital (The Affiliated Hospital of Hunan University), No. 120 Heping Road, Xiangtan 411100, Hunan Province, China. 67324457@qq.com |
Key Words |
Autophagy; Schwann cells; Diabetic peripheral neuropathy; Adenosine monophosphate-activated protein kinase; Mammalian target of rapamycin; Agent |
Core Tip |
This review underscores the critical role of autophagy in Schwann cells (SCs) in the progression of diabetic peripheral neuropathy (DPN) progression, highlight its potential as a pharmacotherapeutic target. It explored autophagy mechanisms (mTOR, AMPK, and PINK/Parkin pathways), their dysregulation in DPN, and various autophagy-modulating agents (natural products and chemical drugs) that promote nerve regeneration and recovery of SCs function. |
Publish Date |
2025-06-13 11:47 |
Citation |
<p>Xing QC, Chen J, Liu Z, Li WC, Liu X, Li W. Autophagy in Schwann cells: A potential pharmacotherapeutic target in diabetic peripheral neuropathy. <i>World J Diabetes</i> 2025; 16(6): 105709</p> |
URL |
https://www.wjgnet.com/1948-9358/full/v16/i6/105709.htm |
DOI |
https://dx.doi.org/10.4239/wjd.v16.i6.105709 |
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