Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	105801
Country	Japan

Received	2025-02-07 03:56
Peer-Review Started	2025-02-07 03:57
To Make the First Decision
Return for Revision	2025-03-04 11:12
Revised	2025-03-07 04:14
Second Decision	2025-04-01 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-04-01 12:00
Articles in Press	2025-04-01 12:00
Publication Fee Transferred
Edit the Manuscript by Language Editor	2025-04-04 01:20
Typeset the Manuscript	2025-05-28 01:22
Publish the Manuscript Online	2025-06-03 08:25

ISSN	2150-5349 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Efficacy of elobixibat for elderly patients with chronic constipation in a clinic
Manuscript Source	Invited Manuscript
All Author List	Yuji Sakai, Toshio Tsuyuguchi, Junichiro Kumagai, Hiroshi Ohyama, Takashi Kaiho, Masayuki Ohtsuka and Naoya Kato
Funding Agency and Grant Number
Corresponding Author	Yuji Sakai, Department of Gastroenterology, Sakai Clinic, 9-18-8 Minamikoyasu, Kimistu 299-1162, Japan. sakai4754@yahoo.co.jp
Key Words	Bile acid; Elderly patients; Elobixibat; Chronic constipation; Post cholecystectomy; Constipation
Core Tip	Elobixibat is effective in improving bowel movements in patients with chronic constipation. Furthermore, there were no significant differences in treatment efficacy or incidence of adverse events between elderly patients and younger patients with chronic constipation. With its high clinical efficacy in treating chronic constipation in elderly patients and its low incidence of adverse events, elobixibat appears to be a viable treatment option for elderly patients.
Publish Date	2025-06-03 08:25
Citation	<p>Sakai Y, Tsuyuguchi T, Kumagai J, Ohyama H, Kaiho T, Ohtsuka M, Kato N. Efficacy of elobixibat for elderly patients with chronic constipation in a clinic. <i>World J Gastrointest Pharmacol Ther</i> 2025; 16(2): 105801</p>
URL	https://www.wjgnet.com/2150-5349/full/v16/i2/105801.htm
DOI	https://dx.doi.org/10.4292/wjgpt.v16.i2.105801

Full Article (PDF)	WJGPT-16-105801-with-cover.pdf
Manuscript File	105801_Auto_Edited_054221.docx
Answering Reviewers	105801-answering-reviewers.pdf
Audio Core Tip	105801-audio.MP3
Biostatistics Review Certificate	105801-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	105801-conflict-of-interest-statement.pdf
Copyright License Agreement	105801-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	105801-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	105801-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	105801-non-native-speakers.pdf
Peer-review Report	105801-peer-reviews.pdf
Scientific Misconduct Check	105801-scientific-misconduct-check.png
Scientific Editor Work List	105801-scientific-editor-work-list.pdf
CrossCheck Report	105801-crosscheck-report.pdf