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6/6/2025 6:59:32 AM | Browse: 18 | Download: 37
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Received |
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2025-02-20 07:04 |
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Peer-Review Started |
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2025-02-20 07:04 |
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To Make the First Decision |
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Return for Revision |
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2025-03-18 19:54 |
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Revised |
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2025-03-29 09:46 |
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Second Decision |
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2025-04-18 02:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-04-18 05:34 |
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Articles in Press |
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2025-04-18 05:34 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-05-30 09:15 |
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Publish the Manuscript Online |
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2025-06-06 03:09 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, General & Internal |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Microbiota geography in the colorectal carcinoma microenvironment: A spatiotemporal atlas of colonic mucosal microbial niche reconstruction
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zong-Qiang Han and Li-Na Wen |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The Beijing High Level Public Health Technology Talent Construction Project |
backbone-03-04 |
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| Corresponding Author |
Li-Na Wen, Associate Research Scientist, Department of Clinical Nutrition, Beijing Shijitan Hospital, Capital Medical University, No. 10 Tieyi Road, Yangfangdian Street, Haidian District, Beijing 100038, China. wenlina3074@bjsjth.cn |
| Key Words |
Microbiota; Colorectal cancer; Colon mucosa; Geography; Case control study |
| Core Tip |
A clinical study from a specific Indonesian population showed that the colonic mucosal microbial composition differs significantly between patients with and without colorectal cancer at the genus and species levels. The combination of Fusobacterium nucleatum and Bacteroides fragilis may serve as a diagnostic biomarker for colorectal cancer. The area under the curve for combined diagnosis was 0.786 (95% confidence interval: 0.671-0.900), with 82.8% sensitivity and 50% specificity. Although the study yielded significant reference results, it was relatively limited in sample size, disease staging, dietary factors, and functional studies of the differential microbiota. Future research should improve on these aspects. |
| Publish Date |
2025-06-06 03:09 |
| Citation |
<p>Han ZQ, Wen LN. Microbiota geography in the colorectal carcinoma microenvironment: A spatiotemporal atlas of colonic mucosal microbial niche reconstruction. <i>World J Gastroenterol</i> 2025; 31(21): 106057</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i21/106057.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i21.106057 |
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