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6/20/2025 8:06:54 AM | Browse: 12 | Download: 24
Publication Name World Journal of Cardiology
Manuscript ID 106147
Country United States
Received
2025-02-17 07:00
Peer-Review Started
2025-02-17 07:01
To Make the First Decision
Return for Revision
2025-03-26 04:21
Revised
2025-04-09 01:41
Second Decision
2025-05-19 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-05-21 13:49
Articles in Press
2025-05-21 13:49
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-06-13 01:21
Publish the Manuscript Online
2025-06-20 07:30
ISSN 1949-8462 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Metabolic-dysfunction associated steatotic liver disease and atrial fibrillation: A review of pathogenesis
Manuscript Source Invited Manuscript
All Author List Inderjeet Singh Bharaj, Ajit Singh Brar, Jasraj Kahlon, Anmol Singh, Priya Hotwani, Vikash Kumar, Aalam Sohal and Akash Batta
Funding Agency and Grant Number
Corresponding Author Aalam Sohal, MD, Department of Gastroenterology and Hepatology, Creighton University School of Medicine, 3216 NE 45th Pl Suite 212, Phoenix, AZ 85012, United States. aalamsohal@gmail.com
Key Words Metabolic-dysfunction associated steatotic liver disease; Non-alcoholic fatty liver disease; Atrial fibrillation; Non-alcoholic steatohepatitis; Insulin resistance; Oxidative stress; Dyslipidemia; Obesity
Core Tip Metabolic dysfunction-associated steatotic liver disease (MASLD) and atrial fibrillation (AF) share common metabolic risk factors, including obesity, diabetes, dyslipidemia, and hypertension. Pathophysiological mechanisms such as systemic inflammation, oxidative stress, insulin resistance, and renin-angiotensin-aldosterone system activation link MASLD to AF. Chronic inflammation and oxidative stress in MASLD lead to atrial remodeling, creating an arrhythmogenic substrate. Effective management of MASLD requires targeted risk-factor modification strategies and a multidisciplinary approach to reduce cardiovascular risk and prevent arrhythmias. Early detection and comprehensive management are crucial to mitigate the dual burden of MASLD and AF.
Publish Date 2025-06-20 07:30
Citation <p>Bharaj IS, Brar AS, Kahlon J, Singh A, Hotwani P, Kumar V, Sohal A, Batta A. Metabolic-dysfunction associated steatotic liver disease and atrial fibrillation: A review of pathogenesis. <i>World J Cardiol</i> 2025; 17(6): 106147</p>
URL https://www.wjgnet.com/1949-8462/full/v17/i6/106147.htm
DOI https://dx.doi.org/10.4330/wjc.v17.i6.106147
Full Article (PDF) WJC-17-106147-with-cover.pdf
Manuscript File 106147_Auto_Edited_062914.docx
Answering Reviewers 106147-answering-reviewers.pdf
Audio Core Tip 106147-audio.mp3
Conflict-of-Interest Disclosure Form 106147-conflict-of-interest-statement.pdf
Copyright License Agreement 106147-copyright-assignment.pdf
Supplementary Material 106147-supplementary-material.pdf
Peer-review Report 106147-peer-reviews.pdf
Scientific Misconduct Check 106147-scientific-misconduct-check.png
Scientific Editor Work List 106147-scientific-editor-work-list.pdf
CrossCheck Report 106147-crosscheck-report.pdf