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6/6/2025 3:38:35 AM | Browse: 10 | Download: 22
Publication Name Artificial Intelligence in Cancer
Manuscript ID 106356
Country China
Received
2025-02-24 10:59
Peer-Review Started
2025-02-24 10:59
To Make the First Decision
Return for Revision
2025-04-02 11:22
Revised
2025-04-02 13:27
Second Decision
2025-04-27 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-04-27 08:41
Articles in Press
2025-04-27 08:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-05-30 03:34
Publish the Manuscript Online
2025-06-06 03:38
ISSN 2644-3228 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Computer Science, Artificial Intelligence
Manuscript Type Retrospective Study
Article Title Can ChatGPT and DeepSeek help cancer patients: A comparative study of artificial intelligence models in clinical decision support
Manuscript Source Invited Manuscript
All Author List Meng Sun, Jun Yu, Jing-Wen Zhou, Ming Ye, Fang Ye and Mei Ding
Funding Agency and Grant Number
Funding Agency Grant Number
Jiangsu Provincial Key R&D Program No. BE2019723
China Academy of Chinese Medical Sciences No. CI2022E028XB
Corresponding Author Fang Ye, . 1596837403@qq.com
Key Words Artificial intelligence; Clinical decision support; Oncology; ChatGPT; DeepSeek; Precision medicine
Core Tip This study compares the efficacy of ChatGPT [a general-purpose artificial intelligence (AI)] and DeepSeek (a domain-specific clinical AI) in oncology decision support. DeepSeek demonstrated superior diagnostic accuracy (F1-score: 89.2% vs 76.5%) and guideline adherence (Cohen’s κ: 0.82 vs 0.67), while ChatGPT excelled in patient communication (readability score: 8.2/10 vs 6.5/10). Both models underperformed in rare cancer subtypes (F1 < 60%), highlighting the need for hybrid systems integrating technical precision and patient-centered communication. This work advocates for AI models tailored to oncology’s heterogeneous demands, with dynamic updates to address evolving clinical guidelines and rare malignancies.
Publish Date 2025-06-06 03:38
Citation <p>Sun M, Yu J, Zhou JW, Ye M, Ye F, Ding M. Can ChatGPT and DeepSeek help cancer patients: A comparative study of artificial intelligence models in clinical decision support. <i>Artif Intell Cancer</i> 2025; 6(1): 106356</p>
URL https://www.wjgnet.com/2644-3228/full/v6/i1/106356.htm
DOI https://dx.doi.org/10.35713/aic.v6.i1.106356
Full Article (PDF) AIC-6-106356-with-cover.pdf
Full Article (Word) 106356.docx
Manuscript File 106356_Auto_Edited_081452.docx
Answering Reviewers 106356-answering-reviewers.pdf
Audio Core Tip 106356-audio.m4a
Conflict-of-Interest Disclosure Form 106356-conflict-of-interest-statement.pdf
Copyright License Agreement 106356-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 106356-non-native-speakers.pdf
Peer-review Report 106356-peer-reviews.pdf
Scientific Misconduct Check 106356-scientific-misconduct-check.png
Scientific Editor Work List 106356-scientific-editor-work-list.pdf
CrossCheck Report 106356-crosscheck-report.pdf