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7/11/2025 8:40:48 AM | Browse: 38 | Download: 94
Publication Name World Journal of Gastroenterology
Manuscript ID 106509
Country China
Received
2025-03-05 07:58
Peer-Review Started
2025-03-05 07:58
To Make the First Decision
Return for Revision
2025-03-18 07:58
Revised
2025-04-29 07:42
Second Decision
2025-06-18 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-06-18 05:50
Articles in Press
2025-06-18 05:50
Publication Fee Transferred
2025-05-06 02:18
Edit the Manuscript by Language Editor
2025-06-23 19:19
Typeset the Manuscript
2025-07-07 05:59
Publish the Manuscript Online
2025-07-11 07:47
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Retrospective Study
Article Title Risk factors and diagnostic biomarkers for asymptomatic immune checkpoint inhibitor-related myocarditis in patients with esophageal cancer after immunotherapy
Manuscript Source Unsolicited Manuscript
All Author List Jing-Yu Liu, Dong-Lai Gao and Xin Cao
Funding Agency and Grant Number
Corresponding Author Xin Cao, Department of Radiotherapy, Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University, No. 3 Employee New Village, Xinghualing District, Taiyuan 030001, Shanxi Province, China. cx18835129589@163.com
Key Words Esophageal cancer; Immune checkpoint inhibitor; Myocarditis; Biomarker; Risk factor; Cardiac monitoring
Core Tip This study investigates the determinants of asymptomatic myocarditis associated with immune checkpoint inhibitors (ICIs) in patients with esophageal cancer. We identified age, gender, and elevated cardiac biomarker levels as significant risk factors for ICI-associated myocarditis. Elevated creatine kinase isoenzymes (CK-MB) and CK levels, along with prolonged QRS duration, were early biomarkers for assessing this condition. Integration of these factors into predictive models may enhance early diagnosis and personalized risk management, improving outcomes for patients receiving immunotherapy.
Publish Date 2025-07-11 07:47
Citation <p>Liu JY, Gao DL, Cao X. Risk factors and diagnostic biomarkers for asymptomatic immune checkpoint inhibitor-related myocarditis in patients with esophageal cancer after immunotherapy. <i>World J Gastroenterol</i> 2025; 31(26): 106509</p>
URL https://www.wjgnet.com/1007-9327/full/v31/i26/106509.htm
DOI https://dx.doi.org/10.3748/wjg.v31.i26.106509
Full Article (PDF) WJG-31-106509-with-cover.pdf
Manuscript File 106509_Auto_Edited_070939.docx
Answering Reviewers 106509-answering-reviewers.pdf
Audio Core Tip 106509-audio.mp3
Biostatistics Review Certificate 106509-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 106509-conflict-of-interest-statement.pdf
Copyright License Agreement 106509-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 106509-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 106509-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 106509-non-native-speakers.pdf
Supplementary Material 106509-supplementary-material.pdf
Peer-review Report 106509-peer-reviews.pdf
Scientific Misconduct Check 106509-scientific-misconduct-check.png
Scientific Editor Work List 106509-scientific-editor-work-list.pdf
CrossCheck Report 106509-crosscheck-report.pdf