Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	106842
Country	Afghanistan

Received	2025-03-09 08:41
Peer-Review Started	2025-03-09 08:41
To Make the First Decision
Return for Revision	2025-04-02 10:54
Revised	2025-04-12 15:57
Second Decision	2025-06-24 02:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-24 07:11
Articles in Press	2025-06-24 07:11
Publication Fee Transferred
Edit the Manuscript by Language Editor	2025-07-08 21:20
Typeset the Manuscript	2025-08-01 07:39
Publish the Manuscript Online	2025-08-14 05:49

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Minireviews
Article Title	Lipid metabolism-related genes in gastric carcinoma: Exploring oncogenic pathways
Manuscript Source	Unsolicited Manuscript
All Author List	Maaz Amir, Danyal Bakht, Syed Faqeer Hussain Bokhari, Rabia Yousaf, Asma Iqbal, Hashir Nazir, Muhammad Waleed, Mustabeen Zahra Naqvi, Maleeha Tahir and Wahidullah Dost
Funding Agency and Grant Number
Corresponding Author	Wahidullah Dost, Researcher, Curative Medicine, Kabul University of Medical Sciences, Karte-e-sakhi Kabul, Kabul 10001, Kabul, Afghanistan. wahidullahdost96@gmail.com
Key Words	Lipid metabolism; Gastric cancer; Oncogenetic pathways; Fatty acid synthesis; Metabolic reprogramming
Core Tip	Dysregulation of lipid metabolism plays a crucial role in gastric cancer progression by supporting tumor growth, migration, and therapy resistance. This review explores the oncogenetic pathways involving key lipid metabolism-associated genes, including fatty acid synthase, ATP-citrate lyase, acetyl-CoA carboxylases, fatty acid binding proteins, and sterol regulatory element-binding proteins, highlighting their role in metabolic reprogramming. Targeting these pathways offers promising therapeutic strategies, as inhibiting lipid biosynthesis enzymes can induce apoptosis and disrupt cancer stem cell properties. Understanding the intricate link between lipid metabolism and gastric carcinoma may pave the way for novel diagnostic and therapeutic advancements.
Publish Date	2025-08-14 05:49
Citation	<p>Amir M, Bakht D, Bokhari SFH, Yousaf R, Iqbal A, Nazir H, Waleed M, Naqvi MZ, Tahir M, Dost W. Lipid metabolism-related genes in gastric carcinoma: Exploring oncogenic pathways. <i>World J Gastrointest Oncol</i> 2025; 17(8): 106842</p>
URL	https://www.wjgnet.com/1948-5204/full/v17/i8/106842.htm
DOI	https://dx.doi.org/10.4251/wjgo.v17.i8.106842

Full Article (PDF)	WJGO-17-106842-with-cover.pdf
Manuscript File	106842_Auto_Edited_010552.docx
Answering Reviewers	106842-answering-reviewers.pdf
Audio Core Tip	106842-audio.mp3
Conflict-of-Interest Disclosure Form	106842-conflict-of-interest-statement.pdf
Copyright License Agreement	106842-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	106842-non-native-speakers.pdf
Peer-review Report	106842-peer-reviews.pdf
Scientific Misconduct Check	106842-scientific-misconduct-check.png
Scientific Editor Work List	106842-scientific-editor-work-list.pdf
CrossCheck Report	106842-crosscheck-report.pdf