| ISSN |
2220-3249 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Health Care Sciences & Services |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Uptake and disparities in tuberculosis screening using urine-lipoarabinomannan among patients with advanced human immunodeficiency virus-disease in Africa: A systematic review
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Lynn Moshi, Hafidha Mhando Bakari, Jackline Vicent Mbishi, Zuhura Mbwana Ally, Mariam Salim Mbwana, Haji Mbwana Ally, Rahma Musoke, Swalehe Mustafa Salim, Maximillian Francis Karia, Leticia Francis Karia, Hassan Fredrick Fussi, Aboubakar Omar Mustafa, Ibrahim Ahmed El-lmam and Habib Omari Ramadhani |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Hafidha Mhando Bakari, Lecturer, Department of Literature, Communication & Publishing, University of Dar es Salaam, President’s Office Regional Administration and Local Government, Ajira Yako, Tanzania, Dar es Salaam NA, Tanzania. fidhat5@gmail.com |
| Key Words |
Tuberculosis testing uptake; Urine lateral flow lipoarabinomannan; Tuberculosis prevalence; Mortality; Africa |
| Core Tip |
Despite its benefit, the utility of lateral flow urine lipoarabinomannan assays in the diagnosis of tuberculosis (TB) among patients with advanced human immunodeficiency virus (HIV) disease in Africa is low. This systematic review analyzed 16055 participants with advanced HIV from nineteen studies involving thirteen countries in Africa. Of the participants eligible to test for TB using lateral flow urine lipoarabinomannan (LF-LAM), only 63% tested with uptake being lower among children compared to adults. Among those diagnosed with TB, 22% died. Nearly four in ten people with advanced HIV disease in Africa tested for TB using LF-LAM per the World Health Organization recommendations, indicating missed opportunity to diagnose TB among patients at high risk of having TB. |
| Publish Date |
2025-09-25 09:22 |
| Citation |
<p>Moshi L, Bakari HM, Mbishi JV, Ally ZM, Mbwana MS, Ally HM, Musoke R, Salim SM, Karia MF, Karia LF, Fussi HF, Mustafa AO, El-lmam IA, Ramadhani HO. Uptake and disparities in tuberculosis screening using urine-lipoarabinomannan among patients with advanced human immunodeficiency virus-disease in Africa: A systematic review. <i>World J Virol</i> 2025; 14(3): 107214</p> |
| URL |
https://www.wjgnet.com/2220-3249/full/v14/i3/107214.htm |
| DOI |
https://dx.doi.org/10.5501/wjv.v14.i3.107214 |
