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11/28/2025 2:03:28 PM | Browse: 15 | Download: 76
Publication Name World Journal of Critical Care Medicine
Manuscript ID 107396
Country United States
Received
2025-03-24 07:39
Peer-Review Started
2025-03-24 07:39
To Make the First Decision
Return for Revision
2025-04-08 05:06
Revised
2025-04-17 02:49
Second Decision
2025-05-27 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-05-27 10:40
Articles in Press
2025-05-27 10:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-11-12 06:18
Publish the Manuscript Online
2025-11-28 14:00
ISSN 2220-3141(online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Critical Care Medicine
Manuscript Type Meta-Analysis
Article Title Safety and early mobilization in intensive care unit patients: An updated systematic review and meta-analysis of randomized controlled trials
Manuscript Source Invited Manuscript
All Author List Syed A Khan, Abdul Moeed, Tahreem Mari, Zehra Yousuf, Arthur Hanson, Yue Dong, Patrick Cornelius, Humayun Anjum, Iqbal Ratnani and Salim Surani
Funding Agency and Grant Number
Corresponding Author Salim Surani, MD, Professor, Department of Medicine and Pharmacology, Texas A&M University, 40 Bizzell Street, College Station, TX 77843, United States. srsurani@hotmail.com
Key Words Early mobilization; Early mobility; Intensive care unit; Critical care unit; Mechanical ventilation; Functional outcomes; Randomized controlled trials; Rehabilitation
Core Tip This updated systematic review and meta-analysis of 16 randomized controlled trials involving 2385 intensive care unit (ICU) patients demonstrates that initiating early mobilization (EM) (within 72 hours of ICU admission) significantly reduces ICU length of stay and mechanical ventilation duration while improving muscle strength and functional status. EM does not increase adverse events or mortality, supporting its safety and efficacy as a routine ICU intervention.
Publish Date 2025-11-28 14:00
Citation <p>Khan SA, Moeed A, Mari T, Yousuf Z, Hanson A, Dong Y, Cornelius P, Anjum H, Ratnani I, Surani S. Safety and early mobilization in intensive care unit patients: An updated systematic review and meta-analysis of randomized controlled trials. <i>World J Crit Care Med</i> 2025; 14(4): 107396</p>
URL https://www.wjgnet.com/2220-3141/full/v14/i4/107396.htm
DOI https://dx.doi.org/10.5492/wjccm.v14.i4.107396
Full Article (PDF) WJCCM-14-107396-with-cover.pdf
PRISMA 2009 Checklist 107396-PRISMA-2009-Checklist.pptx
Manuscript File 107396_Auto_Edited_021730.docx
Answering Reviewers 107396-answering-reviewers.pdf
Audio Core Tip 107396-audio.mp3
Biostatistics Review Certificate 107396-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 107396-conflict-of-interest-statement.pdf
Copyright License Agreement 107396-copyright-assignment.pdf
Supplementary Material 107396-supplementary-material.pdf
Peer-review Report 107396-peer-reviews.pdf
Scientific Misconduct Check 107396-scientific-misconduct-check.png
Scientific Editor Work List 107396-scientific-editor-work-list.pdf
CrossCheck Report 107396-crosscheck-report.pdf