Publication Name	World Journal of Nephrology
Manuscript ID	107415
Country	Pakistan

Received	2025-03-24 05:49
Peer-Review Started	2025-03-31 00:14
To Make the First Decision
Return for Revision	2025-04-14 04:03
Revised	2025-04-16 15:21
Second Decision	2025-06-05 02:50
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-07 02:55
Articles in Press	2025-06-07 02:55
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-07-30 09:29
Publish the Manuscript Online	2025-09-17 08:57

ISSN	2220-6124 (online)
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Category	Urology & Nephrology
Manuscript Type	Minireviews
Article Title	Global emergence of the chikungunya epidemic: A narrative review of the virus-kidney relationship in Pakistan and beyond
Manuscript Source	Invited Manuscript
All Author List	Tabassum Elahi, Muhammed Mubarak, Saima Ahmed and Farzana Rasheed Narejo
Funding Agency and Grant Number
Corresponding Author	Tabassum Elahi, Department of Nephrology, Sindh Institute of Urology and Transplantation, Chand Bibi Road near Civil hospital Karachi, Pakistan, Karachi 74200, Sindh, Pakistan. elahitabassum@gmail.com
Key Words	Chikungunya virus; Acute kidney injury; Chronic kidney disease; Morbidity; Karachi; Public health
Core Tip	Chikungunya virus (CHIKV) has re-emerged as a significant health threat globally, notably in Karachi, Pakistan, exacerbated by urbanization, climate change, and healthcare limitations. While typically presenting with fever, rash, and severe joint pain, CHIKV increasingly shows severe, atypical complications, notably acute kidney injury. Kidney involvement arises from direct viral invasion, immune-mediated inflammation, and exacerbation of pre-existing kidney diseases. Identifying individuals at high risk, especially those with underlying comorbidities, is critical. Understanding CHIKV-induced kidney pathophysiology, including virus-host immune interactions, is essential for timely diagnosis and targeted intervention, ultimately aiming to reduce morbidity, mortality, and improve patient outcomes.
Publish Date	2025-09-17 08:57
Citation	<p>Elahi T, Mubarak M, Ahmed S, Narejo FR. Global emergence of the chikungunya epidemic: A narrative review of the virus-kidney relationship in Pakistan and beyond. <i>World J Nephrol</i> 2025; 14(3): 107415</p>
URL	https://www.wjgnet.com/2220-6124/full/v14/i3/107415.htm
DOI	https://dx.doi.org/10.5527/wjn.v14.i3.107415

Full Article (PDF)	WJN-14-107415-with-cover.pdf
Manuscript File	107415_Auto_Edited_061842.docx
Answering Reviewers	107415-answering-reviewers.pdf
Audio Core Tip	107415-audio.opus
Conflict-of-Interest Disclosure Form	107415-conflict-of-interest-statement.pdf
Copyright License Agreement	107415-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	107415-non-native-speakers.pdf
Peer-review Report	107415-peer-reviews.pdf
Scientific Misconduct Check	107415-scientific-misconduct-check.png
Scientific Editor Work List	107415-scientific-editor-work-list.pdf
CrossCheck Report	107415-crosscheck-report.pdf