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7/7/2025 9:02:23 AM | Browse: 7 | Download: 29
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Received |
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2025-03-25 05:12 |
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Peer-Review Started |
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2025-03-25 05:12 |
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To Make the First Decision |
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Return for Revision |
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2025-04-14 10:02 |
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Revised |
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2025-04-22 10:18 |
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Second Decision |
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2025-05-23 02:46 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-05-24 01:53 |
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Articles in Press |
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2025-05-24 01:53 |
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Publication Fee Transferred |
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2025-04-23 02:51 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-07-02 03:17 |
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Publish the Manuscript Online |
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2025-07-07 05:57 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Otorhinolaryngology |
| Manuscript Type |
Case Report |
| Article Title |
Unexpected metastasis of thyroid cartilage involvement from lung adenocarcinoma: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Mao-Mao Ai, Tao Lin, Ruo-Yu Guo, Ying-Ying Zhang and Feng Yu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Science and Technology Projects in Guangzhou |
2024A03J0563 |
| Science and Technology Projects in Guangzhou |
2023A03J0521 |
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| Corresponding Author |
Mao-Mao Ai, Department of Otorhinolaryngology-Head and Neck Surgery, Guangzhou Red Gross Hospital, Tongfu Middle Road 396 Haizhu District Guangzhou City Guangdong Province, Guangzhou 510220, Guangdong Province, China. maomao6678@126.com |
| Key Words |
Neck neoplasms; Thyroid cartilages; Adenocarcinoma of lung; Case report |
| Core Tip |
This rare case documents thyroid cartilage metastasis from an epidermal growth factor receptor (EGFR)-mutated lung adenocarcinoma (p.E746_S752delinsV) in a 51-year-old smoker. Despite the avascular nature of cartilaginous tissue, the patient presented with neck masses, weight loss, and widespread metastases (pT3N3M1c, stage IVB). First-line gefitinib achieved remarkable regression of cervical, abdominal subcutaneous, and oropharyngeal lesions at 6 months. Key highlights: (1) Thyroid cartilage metastasis, though exceptionally rare, warrants vigilance in lung cancer; (2) EGFR targeting remains effective even in unusual metastatic patterns; and (3) Multidisciplinary management optimizes outcomes. Early molecular testing is critical for tailored therapy. |
| Publish Date |
2025-07-07 05:57 |
| Citation |
<p>Ai MM, Lin T, Guo RY, Zhang YY, Yu F. Unexpected metastasis of thyroid cartilage involvement from lung adenocarcinoma: A case report. <i>World J Clin Cases</i> 2025; 13(25): 107471</p> |
| URL |
https://www.wjgnet.com/2307-8960/full/v13/i25/107471.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v13.i25.107471 |
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