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7/17/2025 10:00:01 AM | Browse: 226 | Download: 307
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Received |
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2025-03-26 04:24 |
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Peer-Review Started |
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2025-03-26 04:24 |
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First Decision by Editorial Office Director |
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2025-04-09 01:50 |
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2025-04-09 01:50 |
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Revised |
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2025-04-18 10:26 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-06-03 02:53 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-06-03 11:19 |
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Articles in Press |
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2025-06-03 11:19 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-07-09 07:17 |
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Publish the Manuscript Online |
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2025-07-17 08:43 |
| ISSN |
2218-5836 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Minireviews |
| Article Title |
Defensive antibacterial coating in orthopaedic surgery: Current evidence and future direction
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Richard Henry Randall Roberts, Charles Gamble and Ibrahim Malek |
| Funding Agency and Grant Number |
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| Corresponding Author |
Richard Henry Randall Roberts, Research Fellow, Department of Trauma and Orthopaedics, Wrexham Maelor Hospital, Croesnewydd Rd, Wrexham LL13 7TD, United Kingdom. richard.roberts@doctors.org.uk |
| Key Words |
Hospital-acquired infections; Surgical site infections; Periprosthetic joint infections; Implant-related infections; Orthopaedic surgery; Antibiotic prophylaxis; Defensive antibacterial coating; Biofilm prevention; Revision arthroplasty; Patient outcomes |
| Core Tip |
Orthopaedic implant-related infections, including prosthetic joint and osteosynthesis-associated infections, significantly burden healthcare systems clinically and economically. Defensive antibacterial coating (DAC®) hydrogel emerges as a promising bioresorbable adjunct to traditional prophylactic strategies, effectively reducing infection rates and antibiotic overuse in orthopaedic surgery. While robust evidence supports DAC® in revision arthroplasty and trauma surgery, further high-quality studies are needed to confirm its role in primary joint replacement and expand applications to diverse patient populations and anatomical sites. |
| Publish Date |
2025-07-17 08:43 |
| Citation |
Roberts RHR, Gamble C, Malek I. Defensive antibacterial coating in orthopaedic surgery: Current evidence and future direction. World J Orthop 2025; 16(7): 107575 |
| URL |
https://www.wjgnet.com/2218-5836/full/v16/i7/107575.htm |
| DOI |
https://dx.doi.org/10.5312/wjo.v16.i7.107575 |
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