Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	107681
Country	China

Received	2025-03-28 07:03
Peer-Review Started	2025-03-28 07:03
To Make the First Decision
Return for Revision	2025-04-11 01:59
Revised	2025-04-21 11:22
Second Decision	2025-06-03 02:47
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-03 07:42
Articles in Press	2025-06-03 07:42
Publication Fee Transferred
Edit the Manuscript by Language Editor	2025-06-09 17:59
Typeset the Manuscript	2025-06-27 08:00
Publish the Manuscript Online	2025-07-14 12:56

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Review
Article Title	Advances and challenges in drug repurposing in precision therapeutics of colorectal cancer
Manuscript Source	Invited Manuscript
All Author List	Xin-Ning Yu, Hua-Tao Wu, Bing-Xuan Wu, Shu-Feng Zhi, Yang-Zheng Lan, Wen-Jia Chen and Jing Liu
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China No. 82273457 Natural Science Foundation of Guangdong Province No. 2023A1515012762 Science and Technology Special Project of Guangdong Province No. 210715216902829
Corresponding Author	Jing Liu, Associate Professor, MD, PhD, The Breast Center, Cancer Hospital of Shantou University Medical College, No. 7 Raoping Road, Shantou 515041, Guangdong Province, China. jliu12@stu.edu.cn
Key Words	Precision therapeutics; Multidisciplinary collaboration; Treatment; Colorectal cancer; Drug repurposing
Core Tip	Drug repurposing emerges as an essential strategy due to its advantages like shorter development timelines and lower costs. This review covers recent progress in repurposing traditional drugs and using high-throughput screening and artificial intelligence for colorectal cancers.
Publish Date	2025-07-14 12:56
Citation	<p>Yu XN, Wu HT, Wu BX, Zhi SF, Lan YZ, Chen WJ, Liu J. Advances and challenges in drug repurposing in precision therapeutics of colorectal cancer. <i>World J Gastrointest Oncol</i> 2025; 17(7): 107681</p>
URL	https://www.wjgnet.com/1948-5204/full/v17/i7/107681.htm
DOI	https://dx.doi.org/10.4251/wjgo.v17.i7.107681

Full Article (PDF)	WJGO-17-107681-with-cover.pdf
Manuscript File	107681_Auto_Edited_065024.docx
Answering Reviewers	107681-answering-reviewers.pdf
Audio Core Tip	107681-audio.mp3
Conflict-of-Interest Disclosure Form	107681-conflict-of-interest-statement.pdf
Copyright License Agreement	107681-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	107681-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	107681-non-native-speakers.pdf
Peer-review Report	107681-peer-reviews.pdf
Scientific Misconduct Check	107681-scientific-misconduct-check.png
Scientific Editor Work List	107681-scientific-editor-work-list.pdf
CrossCheck Report	107681-crosscheck-report.pdf