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8/21/2025 6:52:05 AM | Browse: 218 | Download: 283
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Received |
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2025-04-01 14:56 |
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Peer-Review Started |
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2025-04-01 14:57 |
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To Make the First Decision |
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Return for Revision |
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2025-04-16 10:39 |
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Revised |
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2025-04-30 08:19 |
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Second Decision |
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2025-07-03 02:47 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-07-04 10:06 |
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Articles in Press |
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2025-07-04 10:06 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2025-07-19 17:30 |
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Typeset the Manuscript |
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2025-08-05 09:18 |
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Publish the Manuscript Online |
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2025-08-21 05:29 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Neurosciences |
| Manuscript Type |
Review |
| Article Title |
Therapeutic potential of mesenchymal stem cells in neurodegenerative diseases
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Chen-Xu Cui, Xiao-Nan Shao, Yang-Yang Li, Liang Qiao, Jun-Tang Lin and Li-Hong Guan |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Henan Province |
242300421199, 252300421395 |
| Henan Province Joint Fund for Science and Technology Research and Development |
235101610002 |
| Key Technologies R&D Program of Henan Province |
242102310134 |
| Henan Province Foundation for University Key Teacher |
2024GGJS088 |
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| Corresponding Author |
Li-Hong Guan, Assistant Professor, PhD, Stem Cells and Biotherapy Technology Research Center of Henan, School of Life Science and Technology, Xinxiang Medical University, No. 601 Jinsui Road, Xinxiang 453003, Henan Province, China. lhguan2010@163.com |
| Key Words |
Mesenchymal stem cells; Neurodegenerative disease; Stem cell therapy; Immunomodulation; Paracrine |
| Core Tip |
This review emphasizes the incidence and social burden of neurodegenerative diseases, focusing on the pathogenesis of these diseases and available therapeutic approaches. We have thoroughly investigated the potential of mesenchymal stem cells for use in treating neurodegenerative diseases and explored their therapeutic effects on different diseases. This review aims to elucidate how mesenchymal stem cells can alleviate the progression of neurodegenerative diseases by modulating molecular pathways related to abnormal protein accumulation, neuroinflammation, oxidative stress, and neuroregeneration. |
| Publish Date |
2025-08-21 05:29 |
| Citation |
<p>Cui CX, Shao XN, Li YY, Qiao L, Lin JT, Guan LH. Therapeutic potential of mesenchymal stem cells in neurodegenerative diseases. <i>World J Stem Cells</i> 2025; 17(8): 107717</p> |
| URL |
https://www.wjgnet.com/1948-0210/full/v17/i8/107717.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v17.i8.107717 |
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