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8/12/2025 2:21:09 PM | Browse: 36 | Download: 187
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Received |
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2025-04-03 03:29 |
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Peer-Review Started |
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2025-04-07 05:45 |
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To Make the First Decision |
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Return for Revision |
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2025-05-15 05:51 |
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Revised |
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2025-05-16 15:20 |
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Second Decision |
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2025-07-15 02:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-07-16 03:45 |
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Articles in Press |
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2025-07-16 03:45 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-08-01 02:33 |
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Publish the Manuscript Online |
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2025-08-12 08:18 |
| ISSN |
2220-315x (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Dentistry, Oral Surgery & Medicine |
| Manuscript Type |
Observational Study |
| Article Title |
Genotoxic damage assessment using the micronucleus assay in buccal mucosa of different types of smokers: A cross-sectional study
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Efraín Álvarez-Martínez, Iván E Porto-Puerta and Carlos M Ardila |
| Funding Agency and Grant Number |
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| Corresponding Author |
Carlos M Ardila, Postdoctoral Fellow, Professor, Senior Researcher, Department of Basic Sciences, Biomedical Stomatology Research Group, Faculty of Dentistry, Universidad de Antioquia, U de A, Calle 70 No. 52-21, Medellin 050010, Antioquia, Colombia. martin.ardila@udea.edu.co |
| Key Words |
Oral neoplasms; Smoking; Genotoxicity; Micronucleus; Oral cancer |
| Core Tip |
This study reveals significant genotoxic damage in buccal mucosa cells among conventional, reverse, and electronic cigarette smokers, but not cannabis users, using the micronucleus assay. A strong correlation was found between smoking-related oral lesions and micronucleus frequency, independent of alcohol use. These findings underscore the urgent need for targeted public health strategies to reduce smoking-induced DNA damage and prevent oral carcinogenesis. The results provide critical evidence for policymakers and future research on tobacco-related harm. |
| Publish Date |
2025-08-12 08:18 |
| Citation |
<p>Álvarez-Martínez E, Porto-Puerta IE, Ardila CM. Genotoxic damage assessment using the micronucleus assay in buccal mucosa of different types of smokers: A cross-sectional study. <i>World J Exp Med</i> 2025; 15(3): 108025</p> |
| URL |
https://www.wjgnet.com/2220-315X/full/v15/i3/108025.htm |
| DOI |
https://dx.doi.org/10.5493/wjem.v15.i3.108025 |
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