| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Observational Study |
| Article Title |
Comprehensive study of community acquired Mycoplasma pneumoniae pneumonia in children in Baoding, China, 2023
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Jing Bi, Xu Li, He Tang, Olga Kalinina, Ting-ting Jiang, Wei-wei Jiao, Xi Zeng, Alexander Dmitriev and Adong Shen |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Baoding Science and Technology Plan Project |
2272P011 |
| Hebei Province Scientific Research Project |
20241734 |
| Hebei Natural Science Foundation Project |
H2024104011 |
|
| Corresponding Author |
Adong Shen, Professor, National Clinical Research Center for Respiratory Diseases, Shen, AD (reprint author), Capital Med Univ, Beijing Childrens Hosp, Beijing Pediat Inst, 56 Nan Li Shi Rd, Beijing 100045, Peoples R China., Beijing Pediatric Research Institute, Capital Medical University, Beijing Pediatric Research Institute, Capital Medical University, National Key Discipline of Pediatrics (Capital Medical University), Beijing Pediatric Research Institute, Capital Medical University, Beijing Pediatric Research Institute, Capital Medical University, National Key Discipline of Pediatrics (Capital Medical University), Beijing Pediatric Research Institute, Capital Medical University, Key Laboratory of Pediatric Respiratory Infection Diseases, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, Beijing, 100045, China. shenad16@hotmail.com., Beijing 10045, China. shenad16@hotmail.com |
| Key Words |
Community acquired Mycoplasma pneumoniae pneumonia; Children; Macrolide resistance; A2063G or A2064G mutations |
| Core Tip |
After the lifting of strict non-pharmaceutical interventions (NPIs), the dramatic rise of Mycoplasma pneumoniae pneumonia (MPP) incidence in Europe and Asia was observed. Comprehensive study of community acquired cases of MPP in 2023 in Baoding Hospital, China, was performed. The dramatic increase in the incidence of MPP cases, that was delayed for nine months after lifting NPIs, and unprecedented 93.2% prevalence of macrolide resistant Mycoplasma pneumoniae causing pneumonia in children were revealed. We hypothesized that strict NPIs may have created the “bottleneck” selecting the most successful bacterial clone(s) that subsequently spread, and it may represent a “founder effect”. |
| Publish Date |
2025-10-31 15:02 |
| Citation |
<p>Bi J, Li X, Tang H, Kalinina O, Jiang TT, Jiao WW, Zeng X, Dmitriev A, Shen A. Comprehensive study of community acquired Mycoplasma pneumoniae pneumonia in children in Baoding, China, 2023. <i>World J Clin Pediatr</i> 2025; 14(4): 108047</p> |
| URL |
https://www.wjgnet.com/2219-2808/full/v14/i4/108047.htm |
| DOI |
https://dx.doi.org/10.5409/wjcp.v14.i4.108047 |
