Publication Name	World Journal of Clinical Cases
Manuscript ID	108180
Country	Türkiye

Received	2025-04-09 00:38
Peer-Review Started	2025-04-09 00:39
To Make the First Decision
Return for Revision	2025-05-12 02:11
Revised	2025-05-26 11:03
Second Decision	2025-07-16 02:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-16 23:32
Articles in Press	2025-07-16 23:32
Publication Fee Transferred	2025-06-20 01:22
Edit the Manuscript by Language Editor	2025-07-22 22:39
Typeset the Manuscript	2025-08-01 04:27
Publish the Manuscript Online	2025-08-07 07:38

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Otorhinolaryngology
Manuscript Type	Case Control Study
Article Title	Medial olivocochlear reflex dysfunction in multiple sclerosis: The influence of brainstem lesion localization and its clinical implications
Manuscript Source	Unsolicited Manuscript
All Author List	Ibrahim Salih Gecer, Alper Tabaru, Beyhan Yilmaz, Elif Kaya, Nurhan Kaya Tutar, Bekircan Gumuslu and Mehmet Faruk Oktay
Funding Agency and Grant Number
Corresponding Author	Ibrahim Salih Gecer, Department of Otorhinolaryngology, Istanbul Bakirkoy Research and Training Hospital, Dr. Sadik Ahmet cad no:5 Merkez Mah Bagcilar, Istanbul 34147, Turkey, Türkiye. gecersalih@gmail.com
Key Words	Multiple sclerosis; Inner ear; Hearing loss; Medial olivocochlear reflex; Autoimmune disease
Core Tip	This study provides evidence that the efferent auditory pathway, assessed via the medial olivocochlear (MOC) reflex, is compromised in patients with multiple sclerosis (MS), particularly in those with brainstem lesions. The findings suggest that demyelinating lesions in the brainstem, where the MOC system is anatomically localized, may impair auditory modulation. Temporal cortex involvement appears to have no significant effect. These results support the relevance of efferent auditory evaluation in understanding auditory dysfunctions associated with MS.
Publish Date	2025-08-07 07:38
Citation	<p>Gecer IS, Tabaru A, Yilmaz B, Kaya E, Kaya Tutar N, Gumuslu B, Oktay MF. Medial olivocochlear reflex dysfunction in multiple sclerosis: The influence of brainstem lesion localization and its clinical implications. <i>World J Clin Cases</i> 2025; 13(28): 108180</p>
URL	https://www.wjgnet.com/2307-8960/full/v13/i28/108180.htm
DOI	https://dx.doi.org/10.12998/wjcc.v13.i28.108180

Full Article (PDF)	WJCC-13-108180-with-cover.pdf
STROBE Statement	108180-STROBE-statement.pdf
Manuscript File	108180_Auto_Edited_010829.docx
Answering Reviewers	108180-answering-reviewers.pdf
Audio Core Tip	108180-audio.mp4
Biostatistics Review Certificate	108180-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	108180-conflict-of-interest-statement.pdf
Copyright License Agreement	108180-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	108180-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	108180-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	108180-non-native-speakers.pdf
Peer-review Report	108180-peer-reviews.pdf
Scientific Misconduct Check	108180-scientific-misconduct-check.png
Scientific Editor Work List	108180-scientific-editor-work-list.pdf
CrossCheck Report	108180-crosscheck-report.pdf