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11/4/2025 2:47:55 AM | Browse: 6 | Download: 42
Publication Name World Journal of Psychiatry
Manuscript ID 108591
Country China
Received
2025-04-18 05:19
Peer-Review Started
2025-04-21 00:12
To Make the First Decision
Return for Revision
2025-05-12 02:26
Revised
2025-05-25 16:28
Second Decision
2025-08-11 02:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-08-12 08:45
Articles in Press
2025-08-12 08:45
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-10-20 08:18
Publish the Manuscript Online
2025-11-04 02:41
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychiatry
Manuscript Type Editorial
Article Title Heart rate variability associated with depression and lung decline in chronic obstructive pulmonary disease: Mechanisms and interventions
Manuscript Source Invited Manuscript
All Author List Mei-He Liu and Li-Li Wu
Funding Agency and Grant Number
Corresponding Author Li-Li Wu, Associate Professor, PhD, Department of Developmental Psychology of Armyman, Army Medical University, No. 30 Gaotanyan Zhengjie, Shapingba District, Chongqing 400038, China. wulili080241@163.com
Key Words Chronic obstructive pulmonary disease; Heart rate variability; Depression; Lung function; Underlying mechanisms; Dynamic process; Machine learning
Core Tip The comorbidity of chronic obstructive pulmonary disease and depression severely impacts patients’ health. This editorial explores associations and clinical implications among heart rate variability (HRV), depression, and lung function in chronic obstructive pulmonary disease patients, emphasizing the inflammatory-autonomic-oxidative stress pathway as the core mechanism. It reveals the effects of genetic polymorphisms, environmental factors, and their interactions on HRV differences and comorbidity risk, and further highlights HRV’s longitudinal predictive value in lung function decline and real-time monitoring potential. We propose a comprehensive framework integrating HRV monitoring, multi-omics biomarkers, and machine learning for early intervention and improved patients’ quality of life.
Publish Date 2025-11-04 02:41
Citation <p>Liu MH, Wu LL. Heart rate variability associated with depression and lung decline in chronic obstructive pulmonary disease: Mechanisms and interventions. <i>World J Psychiatry</i> 2025; 15(11): 108591</p>
URL https://www.wjgnet.com/2220-3206/full/v15/i11/108591.htm
DOI https://dx.doi.org/10.5498/wjp.v15.i11.108591
Full Article (PDF) WJP-15-108591-with-cover.pdf
Manuscript File 108591_Auto_Edited_013151.docx
Answering Reviewers 108591-answering-reviewers.pdf
Audio Core Tip 108591-audio.mp3
Conflict-of-Interest Disclosure Form 108591-conflict-of-interest-statement.pdf
Copyright License Agreement 108591-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 108591-non-native-speakers.pdf
Peer-review Report 108591-peer-reviews.pdf
Scientific Misconduct Check 108591-scientific-misconduct-check.png
Scientific Editor Work List 108591-scientific-editor-work-list.pdf
CrossCheck Report 108591-crosscheck-report.pdf