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8/27/2025 11:44:49 AM | Browse: 43 | Download: 69
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Received |
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2025-04-20 03:53 |
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Peer-Review Started |
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2025-04-29 09:02 |
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To Make the First Decision |
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Return for Revision |
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2025-06-03 02:39 |
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Revised |
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2025-06-11 23:04 |
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Second Decision |
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2025-07-15 02:40 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-07-15 07:34 |
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Articles in Press |
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2025-07-15 07:34 |
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Publication Fee Transferred |
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2025-06-13 12:09 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-08-15 03:14 |
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Publish the Manuscript Online |
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2025-08-27 09:21 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Patient factors in responders and non-responders treated with steroids for acute alcohol-associated hepatitis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Kent W Sabatose, Alexandra Baker, Kevin Kugler, Jude Delikat, Bethany Jowers, Ambuj Kumar, Sadaf Aslam, Jacentha Buggs, Christine Machado-Denis, Nyingi Kemmer, Kiran Dhanireddy and Rashid Syed |
| Funding Agency and Grant Number |
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| Corresponding Author |
Rashid Syed, MD, Department of Transplant Hepatology, University of South Florida, Tampa General Medical Group, 409 Bayshore Blvd, Tampa, FL 33606, United States. rashid.syed@gmail.com |
| Key Words |
Acute alcohol-associated hepatitis; Steroids; Transplant; Steroid response; Phosphatidylethanol |
| Core Tip |
Steroid therapy for alcohol-associated hepatitis (AAH) remains the primary therapy despite poor predictability of efficacy. Phosphatidylethanol (PEth) value and other biomarkers were analyzed as predictors of steroid therapy response in the treatment of AAH. PEth value was a poor predictor of steroid therapy response, though pre-steroid biochemical markers of liver response to alcohol consumption significantly correlated with steroid response. Identification of non-responders to steroids can direct these patients to earlier enrollment in liver transplantation and avoid unnecessary medical cost. |
| Publish Date |
2025-08-27 09:21 |
| Citation |
<p>Sabatose KW, Baker A, Kugler K, Delikat J, Jowers B, Kumar A, Aslam S, Buggs J, Machado-Denis C, Kemmer N, Dhanireddy K, Syed R. Patient factors in responders and non-responders treated with steroids for acute alcohol-associated hepatitis. <i>World J Hepatol</i> 2025; 17(8): 108677</p> |
| URL |
https://www.wjgnet.com/1948-5182/full/v17/i8/108677.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v17.i8.108677 |
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