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9/1/2025 9:09:41 AM | Browse: 197 | Download: 158
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Received |
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2025-04-30 03:45 |
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Peer-Review Started |
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2025-04-30 03:45 |
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Return for Revision |
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2025-05-30 18:28 |
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Revised |
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2025-06-27 15:07 |
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Second Decision |
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2025-08-11 02:49 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-08-12 10:09 |
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Articles in Press |
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2025-08-12 10:09 |
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Publication Fee Transferred |
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2025-06-30 13:43 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-08-25 00:43 |
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Publish the Manuscript Online |
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2025-09-01 08:05 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Observational Study |
Article Title |
Methotrexate in the management of Crohn’s disease: A practice survey of gastroenterologists in France
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Guillaume Bonnaud, Jennifer Becker, Myriam Chebbah, Agnès Courbeyrette and Patrick Faure |
Funding Agency and Grant Number |
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Corresponding Author |
Patrick Faure, Hépato-Gastro-Entérologie, Clinique Pasteur, 45 Av. de Lombez BP, Toulouse 31076, France. pfaure@clinique-pasteur.com |
Key Words |
Methotrexate; Crohn’s disease; Combination therapy; Immunosuppressant; Azathioprine; Guidelines; France; Practice survey; Real-world evidence |
Core Tip |
This practice survey among French gastroenterologists reveals a growing confidence in methotrexate (MTX) for managing Crohn’s disease (CD), particularly in combination with biologics for specific patient profiles such as those with joint involvement or Epstein-Barr virus negativity. While MTX is often underutilized compared to azathioprine, respondents acknowledged its favorable long-term safety profile. The study highlights variability in prescribing habits and underlines the need for clearer clinical guidelines and more real-world evidence to support optimal use of MTX in CD. |
Publish Date |
2025-09-01 08:05 |
Citation |
<p>Bonnaud G, Becker J, Chebbah M, Courbeyrette A, Faure P. Methotrexate in the management of Crohn’s disease: A practice survey of gastroenterologists in France. <i>World J Gastroenterol</i> 2025; 31(33): 108872</p> |
URL |
https://www.wjgnet.com/1007-9327/full/v31/i33/108872.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v31.i33.108872 |
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