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10/30/2025 7:50:24 AM | Browse: 20 | Download: 62
Publication Name World Journal of Clinical Cases
Manuscript ID 109020
Country United States
Received
2025-04-28 08:41
Peer-Review Started
2025-04-28 08:41
To Make the First Decision
Return for Revision
2025-05-28 09:46
Revised
2025-06-27 15:22
Second Decision
2025-09-01 02:47
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-09-01 11:25
Articles in Press
2025-09-01 11:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-10-24 05:16
Publish the Manuscript Online
2025-10-30 07:07
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychiatry
Manuscript Type Editorial
Article Title When the diagnosis misses the mark: The psychiatric cost of misdiagnosing hypophosphatasia as fibromyalgia
Manuscript Source Invited Manuscript
All Author List Ethan M Jetter and Brandon P Lucke-Wold
Funding Agency and Grant Number
Corresponding Author Ethan M Jetter, Doctorate Student, College of Medicine, University of Florida, 1600 SW Archer Rd, Gainesville, FL 32601, United States. ejetter@ufl.edu
Key Words Hypophosphatasia; Fibromyalgia; Chronic pain; Alkaline phosphatase; Diagnostic delay; Misdiagnosis; Psychiatric harm; Gender bias; Central sensitization; Patient trust
Core Tip Hypophosphatasia is a rare metabolic bone disease that is susceptible to misdiagnosis as fibromyalgia due to overlapping symptoms such as chronic pain, fatigue, and weakness. This editorial highlights how overlooked low alkaline phosphatase levels and gender bias in pain assessment contribute to diagnostic delays. Greater recognition of hypophosphatasia may help reduce psychiatric harm associated with misdiagnosis.
Publish Date 2025-10-30 07:07
Citation <p>Jetter EM, Lucke-Wold BP. When the diagnosis misses the mark: The psychiatric cost of misdiagnosing hypophosphatasia as fibromyalgia. <i>World J Clin Cases</i> 2025; 13(31): 109020</p>
URL https://www.wjgnet.com/2307-8960/full/v13/i31/109020.htm
DOI https://dx.doi.org/10.12998/wjcc.v13.i31.109020
Full Article (PDF) WJCC-13-109020-with-cover.pdf
Manuscript File 109020_Auto_Edited_084516.docx
Answering Reviewers 109020-answering-reviewers.pdf
Audio Core Tip 109020-audio.mp3
Conflict-of-Interest Disclosure Form 109020-conflict-of-interest-statement.pdf
Copyright License Agreement 109020-copyright-assignment.pdf
Peer-review Report 109020-peer-reviews.pdf
Scientific Misconduct Check 109020-scientific-misconduct-check.png
Scientific Editor Work List 109020-scientific-editor-work-list.pdf
CrossCheck Report 109020-crosscheck-report.pdf