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9/4/2025 7:57:04 AM | Browse: 202 | Download: 91
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Received |
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2025-04-29 04:35 |
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Peer-Review Started |
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2025-04-29 04:35 |
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To Make the First Decision |
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Return for Revision |
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2025-05-18 06:54 |
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Revised |
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2025-05-23 13:47 |
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Second Decision |
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2025-07-01 02:46 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-07-02 06:05 |
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Articles in Press |
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2025-07-02 06:05 |
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Publication Fee Transferred |
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2025-06-01 03:02 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-08-27 07:58 |
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Publish the Manuscript Online |
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2025-09-04 07:48 |
| ISSN |
2150-5349 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Prospective Study |
| Article Title |
Electroacupuncture alleviates symptoms and identifies a potential microbial biomarker in patients with constipation-predominant irritable bowel syndrome
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Kiangyada Yaklai, Chanon Kunasol, Kanokphong Suparan, Nattayaporn Apaijai, Taned Chitapanarux, Sintip Pattanakuhar, Nipon Chattipakorn and Siriporn C Chattipakorn |
| Funding Agency and Grant Number |
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| Corresponding Author |
Siriporn C Chattipakorn, DDS, PhD, Professor, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Muang 50200, Chiang Mai, Thailand. scchattipakorn@gmail.com |
| Key Words |
Irritable bowel syndrome; Traditional Chinese Medicine; Gut microbiota; Constipation; Microbial biomarker |
| Core Tip |
Given the complex pathophysiology of irritable bowel syndrome (IBS), inconsistency of gut microbiota profiles, and the scarce evidence regarding constipation subtype, current treatments often focus on symptom management. Electroacupuncture (EA), as an alternative or complementary approach, has shown clinical efficacy. Our study demonstrated that EA not only alleviated constipation-predominant type (IBS-C) symptoms but also modulated gut dysbiosis and normalized neurotransmitter-related metabolic pathways. Notably, Senegalimassilia was positively linked with clinical improvement, suggesting its potential as a predictive biomarker of EA responsiveness. Additionally, EA offered sustained beneficial therapeutic effects in IBS-C through gut microbiota modulation, supporting its role in clinical practice. |
| Publish Date |
2025-09-04 07:48 |
| Citation |
<p>Yaklai K, Kunasol C, Suparan K, Apaijai N, Chitapanarux T, Pattanakuhar S, Chattipakorn N, Chattipakorn SC. Electroacupuncture alleviates symptoms and identifies a potential microbial biomarker in patients with constipation-predominant irritable bowel syndrome. <i>World J Gastrointest Pharmacol Ther</i> 2025; 16(3): 109046</p> |
| URL |
https://www.wjgnet.com/2150-5349/full/v16/i3/109046.htm |
| DOI |
https://dx.doi.org/10.4292/wjgpt.v16.i3.109046 |
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