Publication Name	World Journal of Gastroenterology
Manuscript ID	109090
Country	Malaysia

Received	2025-04-29 02:42
Peer-Review Started	2025-04-29 02:42
To Make the First Decision
Return for Revision	2025-05-20 19:27
Revised	2025-06-03 16:10
Second Decision	2025-07-08 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-08 03:25
Articles in Press	2025-07-08 03:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-07-27 14:54
Publish the Manuscript Online	2025-08-05 08:25

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Gut-liver axis in diabetes: Mechanisms and therapeutic opportunities
Manuscript Source	Invited Manuscript
All Author List	Mona Mohamed Ibrahim Abdalla
Funding Agency and Grant Number
Corresponding Author	Mona Mohamed Ibrahim Abdalla, MD, PhD, Department of Human Biology, School of Medicine, International Medical University, No. 126 Jln Jalil Perkasa 19, Bukit Jalil 57000, Kuala Lumpur, Malaysia. monamohamed@imu.edu.my
Key Words	Diabetes; Microbiota; Diabetes management; Gut-liver axis; Anti-inflammatory; Intestinal permeability; Metabolic homeostasis
Core Tip	Disruption of the gut-liver axis plays a critical role in the pathophysiology of diabetes by linking gut microbiota alterations, intestinal barrier dysfunction, and inflammatory pathways to hepatic insulin resistance and impaired glucose metabolism. Understanding these mechanisms opens new therapeutic opportunities, including microbiota modulation, gut barrier reinforcement, and targeted anti-inflammatory strategies. These approaches have the potential to significantly improve diabetes management and metabolic outcomes.
Publish Date	2025-08-05 08:25
Citation	<p>Abdalla MMI. Gut-liver axis in diabetes: Mechanisms and therapeutic opportunities. <i>World J Gastroenterol</i> 2025; 31(29): 109090</p>
URL	https://www.wjgnet.com/1007-9327/full/v31/i29/109090.htm
DOI	https://dx.doi.org/10.3748/wjg.v31.i29.109090

Full Article (PDF)	WJG-31-109090-with-cover.pdf
Manuscript File	109090_Auto_Edited_071952.docx
Answering Reviewers	109090-answering-reviewers.pdf
Audio Core Tip	109090-audio.mp3
Conflict-of-Interest Disclosure Form	109090-conflict-of-interest-statement.pdf
Copyright License Agreement	109090-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	109090-non-native-speakers.pdf
Peer-review Report	109090-peer-reviews.pdf
Scientific Misconduct Check	109090-scientific-misconduct-check.png
Scientific Editor Work List	109090-scientific-editor-work-list.pdf
CrossCheck Report	109090-crosscheck-report.pdf