Publication Name	World Journal of Hepatology
Manuscript ID	109093
Country	India

Received	2025-04-29 03:36
Peer-Review Started	2025-05-07 09:17
To Make the First Decision
Return for Revision	2025-05-22 11:22
Revised	2025-06-10 15:28
Second Decision	2025-07-08 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-08 07:01
Articles in Press	2025-07-08 07:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-08-15 03:17
Publish the Manuscript Online	2025-08-27 09:21

ISSN	1948-5182 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Hepatic osteodystrophy: An underrecognized metabolic bone disease
Manuscript Source	Invited Manuscript
All Author List	Subhodip Pramanik, Rajan Palui and Sayantan Ray
Funding Agency and Grant Number
Corresponding Author	Sayantan Ray, Assistant Professor, Department of Endocrinology, All India Institute of Medical Sciences, Sijua, Patrapada, Bhubaneswar 751019, India. sayantan.ray30@gmail.com
Key Words	Hepatic osteodystrophy; Chronic liver disease; Pathogenesis; Management; Vitamin D; Bisphosphonates
Core Tip	Hepatic osteodystrophy (HO) is a common complication, manifested as osteoporosis or osteopenia, encountered in the evolution of chronic liver diseases (CLD). Despite being clinically significant, it often represents an underappreciated and underdiagnosed complication of CLD as systematic screening and management remain suboptimal. The general biology of HO, including its pathogenesis, diagnostic tools, and rationale for treatment, has been determined largely empirically from studies of postmenopausal women with osteoporosis. The treatment of HO is limited, reflecting an unmet need for the best possible management of this disorder. Bisphosphonates have been shown to be effective in selected group of patients with CLD.
Publish Date	2025-08-27 09:21
Citation	<p>Pramanik S, Palui R, Ray S. Hepatic osteodystrophy: An underrecognized metabolic bone disease. <i>World J Hepatol</i> 2025; 17(8): 109093</p>
URL	https://www.wjgnet.com/1948-5182/full/v17/i8/109093.htm
DOI	https://dx.doi.org/10.4254/wjh.v17.i8.109093

Full Article (PDF)	WJH-17-109093-with-cover.pdf
Manuscript File	109093_Auto_Edited_074345.docx
Answering Reviewers	109093-answering-reviewers.pdf
Audio Core Tip	109093-audio.m4a
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Scientific Editor Work List	109093-scientific-editor-work-list.pdf
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