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12/23/2025 8:10:44 AM | Browse: 12 | Download: 40
Publication Name World Journal of Nephrology
Manuscript ID 109099
Country Saudi Arabia
Received
2025-04-29 03:44
Peer-Review Started
2025-05-06 09:22
First Decision by Editorial Office Director
2025-05-17 15:16
Return for Revision
2025-05-17 15:16
Revised
2025-06-09 10:35
Publication Fee Transferred
Second Decision by Editor
2025-09-10 02:48
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-09-10 13:17
Articles in Press
2025-09-10 13:17
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-12-15 08:30
Publish the Manuscript Online
2025-12-23 08:03
ISSN 2220-6124 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Minireviews
Article Title Donor-derived cell-free DNA and its utility in kidney transplantation: A myth or a reality
Manuscript Source Invited Manuscript
All Author List Muhammad Abdul Mabood Khalil, Nihal Mohammed Sadagah, Hinda Hassan Khideer Mahmood, Alfatih Abdalla Altom, Jackson Tan and Salem H Al-Qurashi
Funding Agency and Grant Number
Corresponding Author Muhammad Abdul Mabood Khalil, FRCP, Center of Renal Diseases and Transplantation, King Fahad Armed Forces Hospital Jeddah, Al Kurnaysh Br Road, Al Andalus, Jeddah 23311, Makkah al Mukarramah, Saudi Arabia. doctorkhalil1975@hotmail.com
Key Words Donor-derived cell-free DNA; Rejection; Graft surveillance; Tailoring immunosuppression; Kidney transplantation
Core Tip Donor-derived cell-free DNA is a biomarker for detecting antibody-mediated rejection. It has a potential role for renal allograft surveillance, assessing the immune system reactivity, and monitoring response to rejection therapy. This minireview will focus on its clinical utilization, method of estimation, quantification, and will provide a way for its integration with clinical parameters and gene profiling for its best utility.
Publish Date 2025-12-23 08:03
Citation

Khalil MAM, Sadagah NM, Mahmood HHK, Altom AA, Tan J, Al-Qurashi SH. Donor-derived cell-free DNA and its utility in kidney transplantation: A myth or a reality. World J Nephrol 2025; 14(4): 109099

URL https://www.wjgnet.com/2220-6124/full/v14/i4/109099.htm
DOI https://dx.doi.org/10.5527/wjn.v14.i4.109099
Full Article (PDF) WJN-14-109099-with-cover.pdf
Manuscript File 109099_Auto_Edited_015033.docx
Answering Reviewers 109099-answering-reviewers.pdf
Audio Core Tip 109099-audio.mp3
Conflict-of-Interest Disclosure Form 109099-conflict-of-interest-statement.pdf
Copyright License Agreement 109099-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 109099-non-native-speakers.pdf
Peer-review Report 109099-peer-reviews.pdf
Scientific Misconduct Check 109099-scientific-misconduct-check.png
Scientific Editor Work List 109099-scientific-editor-work-list.pdf
CrossCheck Report 109099-crosscheck-report.pdf