Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	109107
Country	United States

Received	2025-04-30 07:28
Peer-Review Started	2025-04-30 07:28
To Make the First Decision
Return for Revision	2025-05-15 10:14
Revised	2025-05-26 01:55
Second Decision	2025-08-07 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-08-07 06:35
Articles in Press	2025-08-07 06:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-10-11 01:22
Publish the Manuscript Online	2025-10-24 07:36

ISSN	1948-9366 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Surgery
Manuscript Type	Minireviews
Article Title	Fibrolamellar hepatocellular carcinoma: Advances, challenges and opportunities in a rare malignancy
Manuscript Source	Invited Manuscript
All Author List	Leonardo Gomes da Fonseca and Raphael L C Araujo
Funding Agency and Grant Number
Corresponding Author	Raphael L C Araujo, Adjunct Professor, FACS, MD, PhD, Department of Surgery, Universidade Federal de São Paulo, No. 715 Rua Napoleão de Barros, São Paulo 04024-002, Brazil. raphael.l.c.araujo@gmail.com
Key Words	Hepatocellular carcinoma; Fibrolamellar carcinoma; Liver surgery; Systemic treatment; Oncologic outcomes
Core Tip	Fibrolamellar hepatocarcinoma is a rare subtype of primary liver cancer characterized by unique histological, clinical, and molecular features. Although surgical resection remains the cornerstone of curative treatment, advances in molecular biology and identifying specific genetic alterations hold promise for developing targeted therapies, potentially improving outcomes for patients with this rare disease.
Publish Date	2025-10-24 07:36
Citation	<p>da Fonseca LG, Araujo RLC. Fibrolamellar hepatocellular carcinoma: Advances, challenges and opportunities in a rare malignancy. <i>World J Gastrointest Surg</i> 2025; 17(10): 109107</p>
URL	https://www.wjgnet.com/1948-9366/full/v17/i10/109107.htm
DOI	https://dx.doi.org/10.4240/wjgs.v17.i10.109107

Full Article (PDF)	WJGS-17-109107-with-cover.pdf
Manuscript File	109107_Auto_Edited_081041.docx
Answering Reviewers	109107-answering-reviewers.pdf
Audio Core Tip	109107-audio.m4a
Conflict-of-Interest Disclosure Form	109107-conflict-of-interest-statement.pdf
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Peer-review Report	109107-peer-reviews.pdf
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Scientific Editor Work List	109107-scientific-editor-work-list.pdf
CrossCheck Report	109107-crosscheck-report.pdf