Publication Name	World Journal of Gastroenterology
Manuscript ID	109143
Country	India

Received	2025-04-30 04:08
Peer-Review Started	2025-04-30 04:08
To Make the First Decision
Return for Revision	2025-05-27 19:15
Revised	2025-06-08 08:44
Second Decision	2025-08-25 03:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-08-25 06:51
Articles in Press	2025-08-25 06:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-09-11 06:42
Publish the Manuscript Online	2025-09-19 07:57

ISSN	1007-9327 (print) and 2219-2840 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Ultra-processed foods: Implications for gastrointestinal health
Manuscript Source	Invited Manuscript
All Author List	Anupam Kumar Singh, Akash Gandotra, Shubham Kumar, Arjun Singh, Rakesh Kochhar and Manish Manrai
Funding Agency and Grant Number
Corresponding Author	Manish Manrai, FRCPE, Professor, Department of Gastroenterology, Command Hospital, Cariappa Road, Cantonment, Lucknow 226002, Uttar Pradesh, India. manishmanrai75@gmail.com
Key Words	Ultra-processed foods; Gastrointestinal health; Intestinal microbiota; Inflammatory bowel disease; Cancer; Metabolic dysfunction associated steatotic liver disease
Core Tip	Ultra-processed foods (UPFs) are believed to play a role in various chronic inflammatory diseases, such as inflammatory bowel diseases and metabolic syndrome, based on epidemiological studies and emerging preclinical and clinical research. Gastrointestinal (GI) diseases encompass a wide range of disorders with an incomplete understanding of their causes. Often, these disorders are linked to changes in gut microbiota through mechanisms that are not fully understood. The recent development of a new classification for UPFs has improved our understanding of the connection between GI disorders and UPFs. Existing studies indicate that higher consumption of UPFs is associated with increased risks of overweight and obesity, metabolic syndrome, functional GI disorders, inflammatory bowel disease, colorectal cancer, breast cancer, pancreatic cancer, and other cancers. The introduction of this new classification system has expanded our knowledge about the role of ultra-processed foods in various GI disorders and their associations, although this research remains preliminary. Further research is needed to define specific thresholds of UPF intake that could be considered harmful within daily diets. These thresholds should also account for differences across geographical locations and populations.
Publish Date	2025-09-19 07:57
Citation	<p>Singh AK, Gandotra A, Kumar S, Singh A, Kochhar R, Manrai M. Ultra-processed foods: Implications for gastrointestinal health. <i>World J Gastroenterol</i> 2025; 31(36): 109143</p>
URL	https://www.wjgnet.com/1007-9327/full/v31/i36/109143.htm
DOI	https://dx.doi.org/10.3748/wjg.v31.i36.109143

Full Article (PDF)	WJG-31-109143-with-cover.pdf
Manuscript File	109143_Auto_Edited_031743.docx
Answering Reviewers	109143-answering-reviewers.pdf
Audio Core Tip	109143-audio.m4a
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