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11/4/2025 2:47:55 AM | Browse: 6 | Download: 55
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Received |
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2025-05-09 08:10 |
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Peer-Review Started |
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2025-05-09 09:26 |
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To Make the First Decision |
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Return for Revision |
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2025-05-22 10:02 |
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Revised |
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2025-06-04 13:04 |
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Second Decision |
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2025-09-12 02:38 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-09-12 07:10 |
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Articles in Press |
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2025-09-12 07:10 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-10-21 08:08 |
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Publish the Manuscript Online |
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2025-11-04 02:41 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Observational Study |
| Article Title |
Erythrocyte membrane nervonic acid in drug-naive first-episode psychosis and chronic medicated schizophrenia: Implication for impaired myelination and prognosis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Mohammad M Khan |
| Funding Agency and Grant Number |
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| Corresponding Author |
Mohammad M Khan, PhD, Professor, Department of Psychiatry and Health Behavior, Medical College of Georgia, Augusta University, 1460 Laney Walker Blvd, Augusta, GA 30912, United States. mmkhan0@gmail.com |
| Key Words |
Nervonic acid; First-episode psychosis; Chronic schizophrenia; Demyelination; Metabolic abnormalities |
| Core Tip |
Nervonic acid (NA, C24: 1, w9) is a monounsaturated fatty acid that plays a crucial role in myelination and motor function. It also regulates cognitive and metabolic functions, suggesting that impaired NA metabolism may contribute to the pathophysiology of schizophrenia. Although several studies have measured erythrocyte membrane NA in first-episode psychosis, findings are conflicting, and the fate of NA in patients with chronic schizophrenia or under long-term antipsychotic treatment schedule remains unknown. This study was designed to analyze erythrocyte NA composition and its association with psychopathology and metabolic comorbidities in drug-naive patients with first-episode psychosis and antipsychotic-treated patients with chronic schizophrenia. |
| Publish Date |
2025-11-04 02:41 |
| Citation |
<p>Khan MM. Erythrocyte membrane nervonic acid in drug-naive first-episode psychosis and chronic medicated schizophrenia: Implication for impaired myelination and prognosis. <i>World J Psychiatry</i> 2025; 15(11): 109162</p> |
| URL |
https://www.wjgnet.com/2220-3206/full/v15/i11/109162.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v15.i11.109162 |
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