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10/14/2025 8:18:12 AM | Browse: 91 | Download: 144
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 109506
Country China
Received
2025-06-10 09:19
Peer-Review Started
2025-06-10 09:19
To Make the First Decision
Return for Revision
2025-07-01 02:58
Revised
2025-07-10 08:27
Second Decision
2025-08-21 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-08-21 08:04
Articles in Press
2025-08-21 08:04
Publication Fee Transferred
2025-07-14 02:36
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-10-08 09:23
Publish the Manuscript Online
2025-10-14 07:42
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Clinical value of contrast-enhanced ultrasound in early diagnosis of hepatocellular carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Yan Dong, Li-Ping Chen, Jing-Guang He, Qing-Qing Yang and Zhi-Wen Hu
Funding Agency and Grant Number
Funding Agency Grant Number
Science and Technology Program of Chinese Medicine and Integrated Chinese and Western Medicine in Guangzhou 20252A010001
Science and Technology Program of Guangzhou 2024A03J1029
Corresponding Author Zhi-Wen Hu, Department of Medical Ultrasound, Guangzhou First People’s Hospital (Second Affiliated Hospital of South China University of Technology), No. 1 Panfu Road, Guangzhou 510180, Guangdong Province, China. charleyhu@163.com
Key Words Contrast-enhanced ultrasound; Hepatocellular carcinoma; Early diagnosis; Pathological diagnosis; Diagnostic accuracy; Enhancement patterns
Core Tip Contrast-enhanced ultrasound (CEUS) plays an important role in the early diagnosis of hepatocellular carcinoma. By observing characteristic enhancement patterns - such as arterial phase hyperenhancement and portal/delayed phase washout - CEUS provides critical insights into tumor vascularity and behavior. Quantitative indicators such as arterial phase time and peak enhancement intensity further improve diagnostic accuracy. Compared with computed tomography or magnetic resonance imaging, CEUS offers advantages including real-time imaging, lower cost, no ionizing radiation, and better sensitivity for small or early-stage lesions. These strengths support its use in early detection, pathological correlation, and timely clinical intervention for hepatocellular carcinoma.
Publish Date 2025-10-14 07:42
Citation <p>Dong Y, Chen LP, He JG, Yang QQ, Hu ZW. Clinical value of contrast-enhanced ultrasound in early diagnosis of hepatocellular carcinoma. <i>World J Gastrointest Oncol</i> 2025; 17(10): 109506</p>
URL https://www.wjgnet.com/1948-5204/full/v17/i10/109506.htm
DOI https://dx.doi.org/10.4251/wjgo.v17.i10.109506
Full Article (PDF) WJGO-17-109506-with-cover.pdf
Manuscript File 109506_Auto_Edited_032756.docx
Answering Reviewers 109506-answering-reviewers.pdf
Audio Core Tip 109506-audio.mp3
Biostatistics Review Certificate 109506-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 109506-conflict-of-interest-statement.pdf
Copyright License Agreement 109506-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 109506-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 109506-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 109506-non-native-speakers.pdf
Peer-review Report 109506-peer-reviews.pdf
Scientific Misconduct Check 109506-scientific-misconduct-check.png
Scientific Editor Work List 109506-scientific-editor-work-list.pdf
CrossCheck Report 109506-crosscheck-report.pdf