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11/28/2025 2:03:28 PM | Browse: 15 | Download: 55
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Received |
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2025-05-15 06:09 |
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Peer-Review Started |
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2025-05-15 06:10 |
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To Make the First Decision |
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Return for Revision |
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2025-05-20 08:59 |
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Revised |
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2025-05-22 23:04 |
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Second Decision |
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2025-08-05 02:48 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-08-05 11:50 |
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Articles in Press |
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2025-08-05 11:50 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-11-17 04:02 |
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Publish the Manuscript Online |
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2025-11-28 14:00 |
| ISSN |
2220-3141(online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Review |
| Article Title |
Thyroid storm-induced cardiovascular complications and modalities of therapy: Up-to-date review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ayman El-Menyar, Naushad Ahmad Khan, Eman Elmenyar, Başar Cander, Lukasz Szarpak, Vimal Krishnan S, Sagar Galwnkar and Hassan Al-Thani |
| Funding Agency and Grant Number |
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| Corresponding Author |
Ayman El-Menyar, Professor, Department of Surgery, Hamad Medical Corporation, Al-Rayyan Street, Doha 3050, Qatar. aymanco65@yahoo.com |
| Key Words |
Thyroid storm; Thyrotoxicosis; Heart; Thyroid hormones; Cardiovascular System; Heart failure |
| Core Tip |
Endocrine emergencies are potentially reversible clinical entities if identified and picked- up early. These emergencies typically arise from profound dysregulation of the hormone axis, manifesting as either severe hormone deficiency or excess. A thyroid storm, also known as a hyperthyroid crisis or thyrotoxic storm, is a rare but life-threatening endocrine emergency that occurs because of undiagnosed or inadequately treated hyperthyroidism. Thyroid hormones are fundamental to cardiovascular homeostasis, mediated by genomic and non-genomic effects. Thyroid hormone receptors are present in the myocardium and vascular endothelial tissues; thereby, changes in the circulating Thyroid hormone concentration modulate the end-organ activities. This could lead to serious consequences such as cardiomyopathy, heart failure, and life-threatening arrhythmia, ultimately contributing to cardiocirculatory collapse and cardiac death. This review summarizes the current knowledge of pathophysiology and pharmacological and mechanical interventions, ranging from beta-blockers to mechanical and surgical interventions. |
| Publish Date |
2025-11-28 14:00 |
| Citation |
<p>El-Menyar A, Khan NA, Elmenyar E, Cander B, Szarpak L, Krishnan S V, Galwnkar S, Al-Thani H. Thyroid storm-induced cardiovascular complications and modalities of therapy: Up-to-date review. <i>World J Crit Care Med</i> 2025; 14(4): 109565</p> |
| URL |
https://www.wjgnet.com/2220-3141/full/v14/i4/109565.htm |
| DOI |
https://dx.doi.org/10.5492/wjccm.v14.i4.109565 |
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