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8/7/2025 7:39:35 AM | Browse: 270 | Download: 810
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Received |
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2025-05-16 07:47 |
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Peer-Review Started |
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2025-05-16 07:47 |
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First Decision by Editorial Office Director |
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2025-05-26 20:36 |
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2025-05-26 20:36 |
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Revised |
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2025-06-08 16:10 |
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Publication Fee Transferred |
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2025-06-12 10:31 |
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Second Decision by Editor |
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2025-07-02 02:36 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-07-02 05:39 |
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Articles in Press |
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2025-07-02 05:39 |
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Edit the Manuscript by Language Editor |
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2025-07-20 17:52 |
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Typeset the Manuscript |
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2025-08-04 01:36 |
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Publish the Manuscript Online |
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2025-08-07 06:39 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Factors influencing diagnostic delays in celiac disease
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ting Li, Yan Feng, Man Wang, Chun Wang and Feng Gao |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of the Xinjiang Autonomous Region |
2023D01C76 |
| Central Government Guide Local Science and Technology Development Special Fund Project |
ZYYD2024JD1 |
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| Corresponding Author |
Feng Gao, Chief Physician, PhD, Department of Gastroenterology, People’s Hospital of Xinjiang Uygur Autonomous Region, 91 Tianchi Road, Urumqi, Xinjiang, China, Urumqi 830001, China. xjgf0991@163.com |
| Key Words |
Celiac disease; Delayed diagnosis; Restricted cubic splines; Independent risk factors; Blood urea nitrogen |
| Core Tip |
This study presents the largest single-center cohort of Chinese celiac disease (CeD) patients (Marsh ≥ II histopathology) leveraging Xinjiang’s regional referral advantage. Among 166 CeD patients, 42.2% experienced diagnostic delay (> 2 years). Blood urea nitrogen (BUN) was identified as an independent risk factor (OR = 1.29), with risk significantly increasing at ≥ 4.3 mmol/L. Subgroup analyses showed stronger associations of BUN with diagnostic delay in females, patients with non-classical CeD phenotypes, Kazak individuals, and other subgroups. These findings highlight BUN as a novel predictor and provide evidence to prioritize high-risk subgroups for timely screening. |
| Publish Date |
2025-08-07 06:39 |
| Citation |
Li T, Feng Y, Wang M, Wang C, Gao F. Factors influencing diagnostic delays in celiac disease. World J Gastroenterol 2025; 31(30): 109585 |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i30/109585.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i30.109585 |
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