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10/27/2025 11:15:07 AM | Browse: 2 | Download: 14
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Received |
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2025-05-22 09:10 |
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Peer-Review Started |
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2025-05-22 09:20 |
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To Make the First Decision |
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Return for Revision |
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2025-06-13 03:24 |
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Revised |
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2025-07-03 05:17 |
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Second Decision |
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2025-09-04 02:51 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-09-04 06:05 |
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Articles in Press |
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2025-09-04 06:05 |
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Publication Fee Transferred |
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2025-08-11 16:20 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-10-17 06:12 |
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Publish the Manuscript Online |
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2025-10-27 10:57 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Physiology |
| Manuscript Type |
Basic Study |
| Article Title |
Ginger mitigates acrylamide-induced hepatotoxicity through antioxidant and anti-inflammatory mechanisms in rats
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ahmed El-Sayed Nour El Deen, Fatma Rashed, Amira Osman, Osama Khalil Farag, Ahmed F Abdel Ghany, Almoatazbellah Mahmoud Elsayed, Sherif M A Mansour, Mohammed Abdel Aziz Mohammed, Reda S Taha, Sami Ahmed Zaher Basha, Mostafa Mahmoud Youssef Mohamed and Ahmad Taha |
| Funding Agency and Grant Number |
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| Corresponding Author |
Ahmed El-Sayed Nour El Deen, Professor, Department of Physiology, Faculty of Medicine, Al-Azhar University, Grees, Assuit 002, Egypt. a.nourelden@zu.edu.jo |
| Key Words |
Acrylamide; Ginger; Hepatotoxicity; Antioxidants; Oxidative |
| Core Tip |
Acrylamide (ACR), a common toxin in processed foods, poses serious risks to liver health through oxidative stress and inflammation. This study tested whether ginger extract could protect the liver against ACR damage in rats. The results showed that ginger significantly improved liver function, reduced oxidative damage, and supported antioxidant defenses. These findings suggest that ginger may serve as a natural and accessible dietary strategy to protect the liver from toxins found in everyday food. This research highlights the potential of ginger as a safe supplement to prevent food-related liver injury. |
| Publish Date |
2025-10-27 10:57 |
| Citation |
<p>Nour El Deen AES, Rashed F, Osman A, Khalil Farag O, Abdel Ghany AF, Elsayed AM, Mansour SMA, Mohammed MAA, Taha RS, Basha SAZ, Mohamed MMY, Taha A. Ginger mitigates acrylamide-induced hepatotoxicity through antioxidant and anti-inflammatory mechanisms in rats. <i>World J Hepatol</i> 2025; 17(10): 109807</p> |
| URL |
https://www.wjgnet.com/1948-5182/full/v17/i10/109807.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v17.i10.109807 |
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