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8/5/2025 9:52:55 AM | Browse: 219 | Download: 795
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Received |
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2025-05-28 03:59 |
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Peer-Review Started |
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2025-05-28 03:59 |
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First Decision by Editorial Office Director |
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2025-06-05 10:19 |
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Return for Revision |
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2025-06-05 10:19 |
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Revised |
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2025-06-13 15:39 |
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Publication Fee Transferred |
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2025-06-20 11:23 |
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Second Decision by Editor |
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2025-07-08 02:41 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-07-08 03:11 |
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Articles in Press |
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2025-07-08 03:11 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-07-27 14:54 |
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Publish the Manuscript Online |
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2025-08-05 08:25 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Long-term efficacy and short-term outcomes of intersphincteric resection vs abdominoperineal resection in patients with ultra-low rectal cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Guan-Cong Wang, Jun-Xing Chen, Hong-Feng Pan, Kai Ye, Yin-Cong Guo and Ying Huang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Fujian Province |
2023J011819 |
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| Corresponding Author |
Yin-Cong Guo, Chief Physician, Professor, Department of Colorectal Surgery, Zhangzhou Affiliated Hospital of Fujian Medical University, 59
Shengli West Road, Zhangzhou 363000, Fujian Province, China. fjzzgyc@126.com |
| Key Words |
Intersphincteric resection; Abdominoperineal resection; Ultra-low rectal cancer; Propensity score matching; Surgical outcomes |
| Core Tip |
Methodological rigor: As the largest propensity score-matched study comparing intersphincteric resection (ISR) and abdominoperineal resection (APR), we minimized selection bias by balancing 13 covariates across 803 patients (289 matched pairs). Survival advantage: ISR demonstrated a 6.7% absolute improvement in 5-year overall survival (80.8% vs 74.1%, HR = 0.554, P = 0.004) and reduced local recurrence (9.5% vs 12.9%, P = 0.019), establishing its oncologic superiority. Clinical implications: Despite higher anastomotic leakage rates (11.4% vs 1.0%), ISR significantly reduced total complications (29.4% vs 42.2%, P = 0.001) and hospitalization duration (9.8 days vs 12.9 days, P < 0.001), supporting its role as the preferred sphincter-preserving alternative to APR. |
| Publish Date |
2025-08-05 08:25 |
| Citation |
Wang GC, Chen JX, Pan HF, Ye K, Guo YC, Huang Y. Long-term efficacy and short-term outcomes of intersphincteric resection vs abdominoperineal resection in patients with ultra-low rectal cancer. World J Gastroenterol 2025; 31(29): 110004 |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i29/110004.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i29.110004 |
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