Publication Name	World Journal of Hepatology
Manuscript ID	110029
Country	China

Received	2025-06-03 07:05
Peer-Review Started	2025-06-03 07:07
To Make the First Decision
Return for Revision	2025-06-26 07:51
Revised	2025-07-29 15:23
Second Decision	2025-09-29 02:34
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-29 06:04
Articles in Press	2025-09-29 06:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-10-15 07:54
Publish the Manuscript Online	2025-10-27 10:57

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Case Report
Article Title	Unusual presentation of synchronous double primary gallbladder and hepatic malignancies: A case report
Manuscript Source	Invited Manuscript
All Author List	Kun Zhang and Hong-Liang Liu
Funding Agency and Grant Number
Corresponding Author	Hong-Liang Liu, Professor, Department of Hepatobiliary Surgery, Qingdao Women and Children’s Hospital, No. 6 Tongfu Road, Qing Dao 266000, Shandong, China. 1715069155@qq.com
Key Words	Multiple primary cancers; Metastatic cancer; Multidisciplinary team; Diagnosis and treatment; Prognosis; Case report
Core Tip	The synchronous double primary malignancies of the gallbladder and liver represent an exceedingly rare clinical entity with no established management consensus. We present a distinctive case of a 70-year-old patient who achieved no evidence of disease status following multidisciplinary intervention. This case highlights the diagnostic challenges in distinguishing synchronous primaries from metastatic disease, underscores the critical role of histopathological confirmation, and demonstrates the potential for favorable outcomes through aggressive surgical intervention. Our experience provides valuable insights for managing such complex cases.
Publish Date	2025-10-27 10:57
Citation	<p>Zhang K, Liu HL. Unusual presentation of synchronous double primary gallbladder and hepatic malignancies: A case report. <i>World J Hepatol</i> 2025; 17(10): 110029</p>
URL	https://www.wjgnet.com/1948-5182/full/v17/i10/110029.htm
DOI	https://dx.doi.org/10.4254/wjh.v17.i10.110029

Full Article (PDF)	WJH-17-110029-with-cover.pdf
CARE Checklist–2016	110029-CARE-Checklist-2016.pdf
Manuscript File	110029_Auto_Edited_022010.docx
Answering Reviewers	110029-answering-reviewers.pdf
Audio Core Tip	110029-audio.MP3
Conflict-of-Interest Disclosure Form	110029-conflict-of-interest-statement.pdf
Copyright License Agreement	110029-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s)	110029-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate	110029-non-native-speakers.pdf
Peer-review Report	110029-peer-reviews.pdf
Scientific Misconduct Check	110029-scientific-misconduct-check.png
Scientific Editor Work List	110029-scientific-editor-work-list.pdf
CrossCheck Report	110029-crosscheck-report.pdf