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9/11/2025 9:45:46 AM | Browse: 204 | Download: 95
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Received |
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2025-06-03 01:34 |
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Peer-Review Started |
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2025-06-05 00:09 |
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To Make the First Decision |
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Return for Revision |
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2025-06-19 09:07 |
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Revised |
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2025-07-01 08:39 |
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Second Decision |
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2025-08-06 02:38 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-08-15 00:17 |
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Articles in Press |
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2025-08-15 00:17 |
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Publication Fee Transferred |
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2025-07-03 15:05 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-09-03 09:30 |
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Publish the Manuscript Online |
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2025-09-11 09:41 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Radiology, Nuclear Medicine & Medical Imaging |
| Manuscript Type |
Observational Study |
| Article Title |
Magnetic resonance imaging derived biomarkers for the diagnosis of type 2 diabetes with insulin resistance: A pilot study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Bo-Wen Hou, Zheng Ran, Yi-Tong Li, Jing Zhang, Yong-Qiang Chu, Nadeer M Gharaibeh and Xiao-Ming Li |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81930045 |
| National Natural Science Foundation of China |
31630025 |
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| Corresponding Author |
Xiao-Ming Li, PhD, Professor, Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Road, Wuhan 430030, Hubei Province, China. lilyboston2002@tjh.tjmu.edu.cn |
| Key Words |
Type 2 diabetes mellitus; Insulin resistance; Magnetic resonance imaging; Fat infiltration; Muscle |
| Core Tip |
This study reveals that insulin resistance (IR) in type 2 diabetes mellitus exacerbates myosteatosis via intramyocellular lipid (IMCL) accumulation and fat infiltration in paravertebral muscles, alongside vertebral fat fraction increases. Multiparametric magnetic resonance imaging sequences (quantitative Dixon and diffusion tensor imaging) identified key biomarkers (e.g., IMCL, fat-muscle ratios), and erector IMCL specifically showed high diagnostic accuracy for type 2 diabetes mellitus-IR. Multiparametric magnetic resonance imaging evaluation enables non-invasive quantification of early musculoskeletal metabolic injury, providing reliable imaging biomarkers for IR identification and stratification. |
| Publish Date |
2025-09-11 09:41 |
| Citation |
<p>Hou BW, Ran Z, Li YT, Zhang J, Chu YQ, Gharaibeh NM, Li XM. Magnetic resonance imaging derived biomarkers for the diagnosis of type 2 diabetes with insulin resistance: A pilot study. <i>World J Diabetes</i> 2025; 16(9): 110183</p> |
| URL |
https://www.wjgnet.com/1948-9358/full/v16/i9/110183.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v16.i9.110183 |
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