Publication Name	World Journal of Cardiology
Manuscript ID	110278
Country	China

Received	2025-06-11 10:35
Peer-Review Started	2025-06-11 10:35
To Make the First Decision
Return for Revision	2025-06-17 07:51
Revised	2025-06-25 13:26
Second Decision	2025-08-11 02:52
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-08-11 10:19
Articles in Press	2025-08-11 10:19
Publication Fee Transferred	2025-06-27 02:48
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-09-03 08:18
Publish the Manuscript Online	2025-09-17 06:30

ISSN	1949-8462 (online)
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Category	Medical Laboratory Technology
Manuscript Type	Retrospective Cohort Study
Article Title	Correlation of APOE, SLCO1B1 and LPA KIV-2 gene polymorphisms with coronary heart disease in the Teochew population
Manuscript Source	Unsolicited Manuscript
All Author List	Jia-Xin Xu, Ye Wu, Lin Zhang, Yong-Hao Wu, Chun-Lai Li and Fen Lin
Funding Agency and Grant Number	Funding Agency Grant Number Special Research Plan 2023 of Chaozhou 202303GY05
Corresponding Author	Fen Lin, Chief, Professor, Precision Medical Lab Center, Chaozhou Central Hospital, No. 99 Dongshan Road, Chaozhou 521000, Guangdong Province, China. 26395868@qq.com
Key Words	Gene polymorphisms; Coronary heart disease; Teochew population; APOE; SLCO1B1; KIV-2
Core Tip	In this study of 324 patients with coronary heart disease (CHD) and 143 control participants, we analysed polymorphisms in the APOE and SLCO1B1 genes, as well as LPA KIV-2 copy number variation in the Teochew population of southern China. We confirmed that both APOE ɛ2 allele and higher KIV-2 copy number are associated with a reduced risk of CHD in the Teochew population, whereas neither the APOE ɛ4 allele nor SLCO1B1 gene showed any association.
Publish Date	2025-09-17 06:30
Citation	<p>Xu JX, Wu Y, Zhang L, Wu YH, Li CL, Lin F. Correlation of APOE, SLCO1B1 and LPA KIV-2 gene polymorphisms with coronary heart disease in the Teochew population. <i>World J Cardiol</i> 2025; 17(9): 110278</p>
URL	https://www.wjgnet.com/1949-8462/full/v17/i9/110278.htm
DOI	https://dx.doi.org/10.4330/wjc.v17.i9.110278

Full Article (PDF)	WJC-17-110278-with-cover.pdf
STROBE Statement	110278-STROBE-statement.pdf
Manuscript File	110278_Auto_Edited_011642.docx
Answering Reviewers	110278-answering-reviewers.pdf
Audio Core Tip	110278-audio.mp3
Biostatistics Review Certificate	110278-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	110278-conflict-of-interest-statement.pdf
Copyright License Agreement	110278-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	110278-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	110278-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	110278-non-native-speakers.pdf
Peer-review Report	110278-peer-reviews.pdf
Scientific Misconduct Check	110278-scientific-misconduct-check.png
Scientific Editor Work List	110278-scientific-editor-work-list.pdf
CrossCheck Report	110278-crosscheck-report.pdf