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9/17/2025 6:39:47 AM | Browse: 636 | Download: 400
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Received |
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2025-06-11 10:35 |
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2025-06-11 10:35 |
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2025-06-17 07:51 |
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2025-06-17 07:51 |
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2025-06-25 13:26 |
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2025-08-11 02:52 |
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2025-08-11 10:19 |
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2025-09-03 08:18 |
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2025-09-17 06:30 |
| ISSN |
1949-8462 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medical Laboratory Technology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Correlation of APOE, SLCO1B1 and LPA KIV-2 gene polymorphisms with coronary heart disease in the Teochew population
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jia-Xin Xu, Ye Wu, Lin Zhang, Yong-Hao Wu, Chun-Lai Li and Fen Lin |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Special Research Plan 2023 of Chaozhou |
202303GY05 |
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| Corresponding Author |
Fen Lin, Chief, Professor, Precision Medical Lab Center, Chaozhou Central Hospital, No. 99 Dongshan Road, Chaozhou 521000, Guangdong Province, China. 26395868@qq.com |
| Key Words |
Gene polymorphisms; Coronary heart disease; Teochew population; APOE; SLCO1B1; KIV-2 |
| Core Tip |
In this study of 324 patients with coronary heart disease (CHD) and 143 control participants, we analysed polymorphisms in the APOE and SLCO1B1 genes, as well as LPA KIV-2 copy number variation in the Teochew population of southern China. We confirmed that both APOE ɛ2 allele and higher KIV-2 copy number are associated with a reduced risk of CHD in the Teochew population, whereas neither the APOE ɛ4 allele nor SLCO1B1 gene showed any association. |
| Publish Date |
2025-09-17 06:30 |
| Citation |
Xu JX, Wu Y, Zhang L, Wu YH, Li CL, Lin F. Correlation of APOE, SLCO1B1 and LPA KIV-2 gene polymorphisms with coronary heart disease in the Teochew population. World J Cardiol 2025; 17(9): 110278 |
| URL |
https://www.wjgnet.com/1949-8462/full/v17/i9/110278.htm |
| DOI |
https://dx.doi.org/10.4330/wjc.v17.i9.110278 |
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