BPG is committed to discovery and dissemination of knowledge
Featured Articles
12/25/2025 9:24:08 AM | Browse: 7 | Download: 22
Publication Name World Journal of Stem Cells
Manuscript ID 110894
Country United States
Received
2025-06-18 10:26
Peer-Review Started
2025-06-18 10:26
First Decision by Editorial Office Director
2025-07-08 06:40
Return for Revision
2025-07-08 06:40
Revised
2025-07-18 20:05
Publication Fee Transferred
2025-07-21 14:34
Second Decision by Editor
2025-11-04 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-12 04:13
Articles in Press
2025-11-12 04:13
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-12-18 00:21
Publish the Manuscript Online
2025-12-25 03:52
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Basic Study
Article Title Isolation and characterization of CD73+CD39+CD146+ mesenchymal stem cell subset from bone marrow
Manuscript Source Unsolicited Manuscript
All Author List Kathryn Martin and Francesca Gullo
Funding Agency and Grant Number
Corresponding Author Kathryn Martin, Researcher, Research & Development, Gift of Life Center for Cell and Gene Therapy, 5901 Broken Sound Parkway NW, Boca Raton, FL 33487, United States. kattmart80@gmail.com
Key Words Hematopoietic stem cells; Bone marrow-derived mesenchymal stem cells; Mesenchymal stem cells; Mesenchymal stem cell-like pericytes; Hematopoietic stem cell transplants; Peripheral blood stem cells; Single and dual mobilized leukopaks
Core Tip In this study, the co-expression of CD73, CD39, and CD146 enabled the identification and enrichment of a mesenchymal stem cell subset with pericyte-like properties from bone marrow cultures. This subset was also found in mobilized blood of adult donors, which serve as a source for allogenic stem cell transplants. Since pericytes are known to play a vital role in maintaining hematopoiesis in vivo, we anticipate that using this subset in a co-culture system with hematopoietic stem cells could potentially lead, with further investigation, to methods for expanding hematopoietic stem cells and creating an inventory of products that are readily available for transplants.
Publish Date 2025-12-25 03:52
Citation

Martin K, Gullo F. Isolation and characterization of CD73+CD39+CD146+ mesenchymal stem cell subset from bone marrow. World J Stem Cells 2025; 17(12): 110894

URL https://www.wjgnet.com/1948-0210/full/v17/i12/110894.htm
DOI https://dx.doi.org/10.4252/wjsc.v17.i12.110894
Full Article (PDF) WJSC-17-110894-with-cover.pdf
Manuscript File 110894_Auto_Edited_021836.docx
Answering Reviewers 110894-answering-reviewers.pdf
Audio Core Tip 110894-audio.mp3
Biostatistics Review Certificate 110894-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 110894-conflict-of-interest-statement.pdf
Copyright License Agreement 110894-copyright-assignment.pdf
Institutional Review Board Approval Form or Document 110894-institutional-review-board-statement.pdf
Supplementary Material 110894-supplementary-material.pdf
Peer-review Report 110894-peer-reviews.pdf
Scientific Misconduct Check 110894-scientific-misconduct-check.png
Scientific Editor Work List 110894-scientific-editor-work-list.pdf
CrossCheck Report 110894-crosscheck-report.pdf