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11/6/2025 9:06:02 AM | Browse: 11 | Download: 21
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Received |
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2025-06-26 09:13 |
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Peer-Review Started |
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2025-06-26 09:13 |
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To Make the First Decision |
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Return for Revision |
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2025-07-03 11:15 |
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Revised |
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2025-08-03 16:14 |
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Second Decision |
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2025-10-14 02:46 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-10-14 07:32 |
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Articles in Press |
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2025-10-14 07:32 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-10-29 00:57 |
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Publish the Manuscript Online |
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2025-11-06 08:56 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Mechanisms of ferroptosis in primary hepatocellular carcinoma and progress of artificial intelligence-based predictive modeling in hepatocellular carcinoma
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Jiang-Feng Han, Zi-Yao Jia, Xiang Fan, Xue-Yan Zhao, Li-Ye Cheng, Yu-Xuan Xia, Xiao-Ran Ji and Wen-Qiao Zang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Henan Provincial Science and Technology Research Project |
252102311168, 242102310066 |
| Medical Education Research Project in Henan Province |
WJLX2024153 |
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| Corresponding Author |
Wen-Qiao Zang, Professor, College of Basic Medical Sciences, Zhengzhou University, No. 100 Kexue Road, Zhengzhou 450000, Henan Province, China. zangwenqiao@zzu.edu.cn |
| Key Words |
Ferroptosis; Liver cancer; Sorafenib; Ferroptosis-related enzymes; Artificial intelligence prediction model; Ferroptosis-related noncoding RNAs |
| Core Tip |
The molecular mechanisms of ferroptosis have been systematically investigated, and this review further summarizes the potential applications of targeting ferroptosis in liver cancer treatment. Not only does this review cover the anticancer drugs such as sorafenib and the mechanisms of action of related enzymes, but it also provides a comprehensive overview of the potential therapeutic strategies in this context. In addition, based on the rapid advancement of artificial intelligence-driven prediction models for liver cancer in recent years, this review discusses various types of artificial intelligence-based prediction models, aiming to provide new insights into the development of robust predictive tools for liver cancer. |
| Publish Date |
2025-11-06 08:56 |
| Citation |
<p>Han JF, Jia ZY, Fan X, Zhao XY, Cheng LY, Xia YX, Ji XR, Zang WQ. Mechanisms of ferroptosis in primary hepatocellular carcinoma and progress of artificial intelligence-based predictive modeling in hepatocellular carcinoma. <i>World J Gastroenterol</i> 2025; 31(41): 111174</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i41/111174.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i41.111174 |
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