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3/6/2026 9:14:49 AM | Browse: 7 | Download: 16
Publication Name World Journal of Clinical Pediatrics
Manuscript ID 111304
Country India
Received
2025-07-01 02:30
Peer-Review Started
2025-07-01 02:30
First Decision by Editorial Office Director
2025-07-11 09:11
Return for Revision
2025-07-11 09:11
Revised
2025-07-24 16:30
Publication Fee Transferred
Second Decision by Editor
2025-10-29 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-29 08:48
Articles in Press
2025-10-29 08:48
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-22 09:01
Publish the Manuscript Online
2026-03-06 08:56
ISSN 2219-2808 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pediatrics
Manuscript Type Randomized Controlled Trial
Article Title Balanced electrolyte solution vs isotonic saline in the resuscitation of children with diabetic ketoacidosis: A randomized controlled trial
Manuscript Source Invited Manuscript
All Author List Sweta Sweety, Swarupa Panda and Rashmi Ranjan Das
Funding Agency and Grant Number
Corresponding Author Rashmi Ranjan Das, FCCP, MD, Professor, Department of Pediatrics, All India Institute of Medical Sciences, Department of Pediatrics, All India Institute of Medical Sciences, Bhuvaneshwar, Odisha, India. Electronic address: ped_rashmi@aiimsbhubaneswar.edu.in, Bhubaneswar 751019, Odisha, India. ped_rashmi@aiimsbhubaneswar.edu.in
Key Words Crystalloids; Hyperglycemia; Hyperchloremia; Acidosis; Acute kidney injury
Core Tip The management of childhood diabetic keto-acidosis (DKA) is fluid resuscitation in addition to insulin infusion. There is a controversy regarding the ideal fluid for the management of DKA. This trial compared balanced electrolyte solution (BES) with normal saline (NS), and found no difference between the two. However, a trend towards lower complication rate was noted with BES. BES might be preferred over NS for initial management of children with DKA where resource constraint is not an issue.
Publish Date 2026-03-06 08:56
Citation

Sweety S, Panda S, Das RR. Balanced electrolyte solution vs isotonic saline in the resuscitation of children with diabetic ketoacidosis: A randomized controlled trial. World J Clin Pediatr 2026; 15(1): 111304

URL https://www.wjgnet.com/2219-2808/full/v15/i1/111304.htm
DOI https://dx.doi.org/10.5409/wjcp.v15.i1.111304
Full Article (PDF) WJCP-15-111304-with-cover.pdf
CONSORT 2010 Statement 111304-CONSORT-2010-statement.pdf
Manuscript File 111304_Auto_Edited_020156.docx
Answering Reviewers 111304-answering-reviewers.pdf
Audio Core Tip 111304-audio.m4a
Biostatistics Review Certificate 111304-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 111304-conflict-of-interest-statement.pdf
Copyright License Agreement 111304-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 111304-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 111304-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 111304-non-native-speakers.pdf
Peer-review Report 111304-peer-reviews.pdf
Scientific Misconduct Check 111304-scientific-misconduct-check.png
Scientific Editor Work List 111304-scientific-editor-work-list.pdf
CrossCheck Report 111304-crosscheck-report.pdf