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12/5/2025 11:30:28 AM | Browse: 35 | Download: 58
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Received |
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2025-07-01 09:26 |
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Peer-Review Started |
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2025-07-01 09:26 |
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2025-07-14 07:39 |
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2025-07-14 07:39 |
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2025-07-16 17:11 |
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2025-07-17 15:51 |
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Second Decision by Editor |
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2025-10-09 02:35 |
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Final Decision by Editorial Office Director |
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2025-10-10 06:44 |
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Articles in Press |
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2025-10-10 06:44 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-11-25 05:13 |
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Publish the Manuscript Online |
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2025-12-05 11:28 |
| ISSN |
2150-5349 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pharmacology & Pharmacy |
| Manuscript Type |
Review |
| Article Title |
Targeted nanoliposomal nutrient delivery for human health
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Joseph Mercola |
| Funding Agency and Grant Number |
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| Corresponding Author |
Joseph Mercola, Researcher, . drm@mercola.com |
| Key Words |
Nanoliposomal delivery; Nutrient bioavailability; Targeted supplementation; Mitochondrial targeting; Receptor mediated endocytosis; Endosomal escape; Oral lymphatic transport; Polyethylene glycol limitations; Coenzyme Q10; Precision nutrition |
| Core Tip |
By enclosing nutrients in nanoscale liposomes, this review shows how bioavailability leaps past gastric destruction, intestinal mucus, and first-pass metabolism while programmable surfaces steer payloads directly to kidneys, brain, or even mitochondria via ligands such as SS-31. The authors detail pH-responsive, fusogenic designs that escape endosomes, contrast natural lipid shells with immunogenic PEGylation, and map translational paths from coenzyme Q10 to heavy-metal chelation. Together, targeted nanoliposomal delivery promises drug-level precision nutrition without drug-level costs, redefining supplement science. |
| Publish Date |
2025-12-05 11:28 |
| Citation |
Mercola J. Targeted nanoliposomal nutrient delivery for human health. World J Gastrointest Pharmacol Ther 2025; 16(4): 111502 |
| URL |
https://www.wjgnet.com/2150-5349/full/v16/i4/111502.htm |
| DOI |
https://dx.doi.org/10.4292/wjgpt.v16.i4.111502 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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